Prostate Cancer Clinical Trial
Official title:
The Impact of Antioxidants on MRI Markers of Cell Proliferation and Hypoxia Among Men on Active Surveillance With Early Stage Prostate Cancer
Verified date | February 2018 |
Source | University Health Network, Toronto |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to determine whether antioxidants (vitamin E, selenium and lycopene)can change(reduce)prostate tumor size or blood flow to the prostate as determined by MRI imaging among men on Active Surveillance.
Status | Completed |
Enrollment | 16 |
Est. completion date | December 2013 |
Est. primary completion date | December 2013 |
Accepts healthy volunteers | No |
Gender | Male |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - MRI detectable prostate cancer - PSA less than 15 ng/ml - Gleason score <= 7 - Prostate cancer staging T1c or T2a Exclusion Criteria: - Concurrent use of high-dose vitamins which include selenium, lycopene, vitamin D or vitamin E - Other malignancies diagnosed or requiring treatment within the past 5 years (except superficial bladder cancer or basal cell carcinoma) - Current use of Proscar or Avodart |
Country | Name | City | State |
---|---|---|---|
Canada | University Health Network - Princess Margaret Hospital | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
University Health Network, Toronto | The Prostate Cancer Research Foundation of Canada |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | To determine the impact of combination vitamin E, lycopene, and selenium on MRI detected prostate tumor size and/or tumor blood flow among me on active surveillance | At baseline MRI compared to 1-year MRI compared to 2-year MRI |
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