Prostate Cancer Clinical Trial
Official title:
A Phase II Study of Mifepristone (RU-486) in Androgen Independent Prostate Cancer With Correlative Assessment of Androgen Receptor Co-Repressor Proteins
The purpose of this study is to determine the effects (good and bad) that mifepristone has on patients with androgen independent prostate cancer.
Patients will receive mifepristone, 200mg orally once a day. One treatment cycle is 28 days
long. Patients will remain on treatment unless their cancer gets worse or they develop
intolerable side effects.
At the end of each cycle a physical examination, routine blood tests, and hormone levels
will be performed.
After every 3 cycles, one or more of the following will be performed: bone scan, chest
x-ray, CT scan or MRI.
;
Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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