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Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer — SOAR  

Prostate Adenocarcinoma Clinical Trial

Official title:
Salvage Oligometastasectomy and Radiation Therapy in Recurrent Prostate Cancer (SOAR)

Clinical Trial Summary

This phase II trial studies how well surgery and radiation therapy work in treating patients with prostate cancer that has come back or spread to other parts of the body. Radiation therapy uses high energy beams to kill tumor cells and shrink tumors. Surgical procedures, such as oligometastasectomy, may remove tumor cells that have spread to other parts of the body. Surgery and radiation therapy may work better in treating patients with prostate cancer that has come back or spread to other parts of the body.

Clinical Trial Description

PRIMARY OBJECTIVES: I. To assess response to treatment of oligometastatic disease. SECONDARY OBJECTIVES: I. To assess additional measurements of response to treatment of oligometastatic disease. II. To assess prostate-specific antigen (PSA) progression free-survival following treatment of oligometastatic disease. III. To assess time to disease recurrence following treatment of oligometastatic disease. IV. To assess time to initiation of antiandrogen therapy (ADT) for metastatic prostate cancer following treatment of oligometastatic disease. V. To assess the rate of undetectable PSA following treatment of oligometastatic disease in subjects who have previously undergone prostatectomy. VI. To assess safety. VII. To assess the impact of study treatment on change in quality of life over three years. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03796767
Study type Interventional
Source University of Utah
Contact
Status Active, not recruiting
Phase Phase 2
Start date September 9, 2019
Completion date June 30, 2026
View Details
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