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Clinical Trial Summary

This phase II trial studies how well apalutamide works in treating patients with prostate cancer who are in active surveillance. Testosterone can cause the growth of prostate cancer cells. Hormone therapy using androgen receptor antagonist apalutamide may fight prostate cancer by blocking the use of testosterone by the tumor cells.


Clinical Trial Description

OUTLINE: Patients receive apalutamide orally (PO) once daily (QD) for 90 days in the absence of disease progression or unacceptable toxicity. After completion of the study treatment, patients are followed up at 180, 365, 545, and 730 days; and at years 3, 4 and 5 by medical record review. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02721979
Study type Interventional
Source University of Washington
Contact
Status Terminated
Phase Phase 2
Start date November 2, 2017
Completion date November 30, 2021

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