The Usefulness of CaIMR in Patients With STEMI

Status Not yet recruiting

Clinical Trial Summary

The coronary artery system is composed of three different types of blood vessels, namely epicardial arteries, arterioles and capillaries. Compared with epicardial arteries, arterioles and capillaries are lower than the resolution of current angiography systems, so angiography cannot be used for visualization. Existing studies have shown that coronary microcirculation plays an extremely important role in maintaining full myocardial perfusion. Coronary microvascular disorders can lead to myocardial hypoperfusion and ischemia, and are related to the poor prognosis of patients with coronary heart disease. At present, there is no technology that can directly detect the state of the coronary microcirculation in the human body, but the coronary microcirculation function can be indirectly assessed through two invasive and non-invasive methods. Among them, the index of microcirculation resistance (IMR) is widely used to evaluate coronary microcirculation function [3]. However, in the case of epicardial stenosis, accurate determination of IMR requires knowledge of coronary artery contraction pressure (Pw). However, measuring IMR is an invasive examination technique, and measuring IMR requires high technical requirements for the operator. Therefore, the CaIMR value obtained by AI technology can well overcome this limitation, and the existing data show that the CaIMR value has a good correlation with the IMR value. However, CaIMR has a clinical prognosis for patients with acute ST-segment elevation myocardial infarction. The predictive value of CaIMR has not yet been explored. This project aims to evaluate the application value of CaIMR in predicting the occurrence of adverse cardiovascular events in patients with acute ST-segment elevation myocardial infarction after percutaneous coronary intervention.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Infarction
Myocardial Infarction
Prognosis
ST Elevation Myocardial Infarction
ST-segment Elevation Myocardial Infarction

Clinical Trial Details

NCT number	NCT04984915
Study type	Observational
Source	Zhongnan Hospital
Contact	Zhibing Lu, MD, PhD
Phone	8615997405817
Email	luzhibing222@163.com
Status	Not yet recruiting
Phase
Start date	May 15, 2022
Completion date	December 1, 2023

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04101448` - Prevalence of Bronchiectasis in COPD Patients
Recruiting	`NCT03635619` - The Application of 3T MRI in Esophageal Cancer
Recruiting	`NCT04377854` - Prognostic Value of BNP in MCS - a 25 Year Follow up Study
Completed	`NCT05586828` - A Single-center Retrospective Cohort Study to Explore the Prognostic Significance of CONUT in Elderly CAD Patients With HFpEFand Compare CONUT With Other Objective Nutritional Indices.
Enrolling by invitation	`NCT04517981` - Cohort Study on the Outcome and Influencing Factors of Perinatal Depression
Recruiting	`NCT05229328` - Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Sepsis
Completed	`NCT04470440` - Thyroid Dysfunction and Nivolumab Reponse in NSCLC
Recruiting	`NCT05848310` - Preoperative Serum FGF19 in the Prognosis of Biliary Atresia
Completed	`NCT02582333` - Clinical Course Study in Chronic Hepatitis B After Nucleos(t)Ide Analogue Therapy
Completed	`NCT03652402` - Precision Risk Stratification in Kidney Transplant Patients - EU-TRAIN
Recruiting	`NCT04651933` - A Training Set for the HRD Model in EOC
Completed	`NCT04651920` - A Study on Association Between HR Genes and the HRD Status in Chinese Epithelial Ovarian Cancer
Recruiting	`NCT03843905` - Predictive Value of Innovative Prognostic Markers (Gut Microbiota, Sarcopenia, Metabolic Syndrome and Obesity) on Surgical and Oncologic Results in the Management of Sporadic Colorectal Adenocarcinoma.
Completed	`NCT05620537` - A Novel Nomogram to Predict the Postoperative Overall Survival in Gastrointestinal Cancer Patients
Recruiting	`NCT03738319` - Non-coding RNA in the Exosome of the Epithelia Ovarian Cancer
Recruiting	`NCT03742869` - HPV Integration and Tumorigenesis of Uterine Cervical Adenocarcinoma
Completed	`NCT03268096` - Disability, MRI Lesions and Thickness of Retinal Fibers: Evaluation 15 Years After a First Episode of Demyelination
Recruiting	`NCT04004559` - MRI Radiomics Assessing Neoadjuvant Chemotherapy in Breast Cancer to Predict Lymph Node Metastasis and Prognosis(RBC-02)
Recruiting	`NCT05494502` - Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients	N/A
Recruiting	`NCT04411563` - Epigenetic Tools as Prognostic Predictors in Covid19

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.