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Molecular Imaging of HER2 Expression in Breast Cancer Using [123I] I-(HE)3-G3

Primary Breast Cancer Clinical Trial

Official title:
SPECT Imaging of Human Epidermal Growth Factor Receptor 2 (HER2) Expression in Breast Cancer Using Iodine -123-labelled Designed Ankyrin Repeat Proteins HE3-G3 ([123I] I-(HE)3-G3)

Clinical Trial Summary

The study should evaluate distribution of [123I] I-(HE)3-G3 in patients with primary HER2-positive and HER2-negative breast cancer

Clinical Trial Description

Overall goal of the project: To determine HER2 expression level in primary breast cancer before neoadjuvant system therapy. Phase I. Distribution of HE3-G3 ([123I] I-(HE)3-G3) in patients with primary breast cancer. The study should evaluate distribution of HE3-G3 ([123I] I-(HE)3-G3) in patients with primary HER2-positive and HER2-negative breast cancer. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05923177
Study type Interventional
Source Tomsk National Research Medical Center of the Russian Academy of Sciences
Contact Olga Bragina, Dsc
Phone +79627761423
Email rungis@mail.ru
Status Recruiting
Phase Phase 1
Start date September 1, 2023
Completion date September 1, 2024
View Details
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