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Clinical Trial Summary

Current standard therapy of primary biliary cholangitis-autoimmune hepatitis overlap syndrome(PBC-AIH overlap) consists of a combination of prednisolone and azathioprine. However, a significant proportion of patients may do not respond to, or is intolerant for azathioprine. Several studies have documented the efficacy and safety of mycophenolate mofetil(MMF) as second-line therapy for PBC-AIH overlap. However, robust evidence from a formal randomized clinical trial for the first-line immunosuppressor is in need.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04933292
Study type Interventional
Source West China Hospital
Contact Xiaoli Fan, Master degree
Phone +86 13980433451
Email 13980433451@163.com
Status Recruiting
Phase Phase 4
Start date June 16, 2021
Completion date May 2022

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