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Preterm clinical trials

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NCT ID: NCT05805254 Completed - Preterm Clinical Trials

Neurofunctional Study of Preterm Infants' Brain Activity

Start date: March 25, 2018
Phase:
Study type: Observational

During hospital stay, a family centered therapeutic approach is increasingly seen as the preferred clinical and care model to be adopted, since it is effective in promoting the neurobehavioral development of the infant and the psychophysical health of the family. In preterm infant, parental relationship and parental relationship-centered interventions, such as kangaroo mother care (KMC), are actively promoted. Studies carried out with electroencephalography showed that preterm infants who participated in KMC interventions have, when reach term equivalent age, a similar level of maturity as healthy full-term infants. It has also been observed that KMC carried out in preterm infant with gestational age <33 weeks promotes adequate development of the primary motor cortex during adolescence. Recent scientific evidence showed an early response to relational stimulations, in particular to their emotional content, of term infants. After few days of life, the infant's brain picks up messages from the human context and interacts with them. For example, a study using near-infrared spectroscopy (NIRS) showed increased activation of the right frontal cortex in infants in association with their mother's direct speech. Similar neuroimaging studies have not yet been conducted in preterm infants during hospitalization. The aim of this study is to assess the activation of the cerebral cortex of the preterm infant in the course of 1) KMC and 2) listening to their mother's voice, using optical topography, a multichannel NIRS system.

NCT ID: NCT05513768 Completed - Preterm Clinical Trials

PRETERM DELİVERY and MYOCINE BINDING PROTEIN C LEVELs

Start date: January 1, 2022
Phase:
Study type: Observational

IT WAS AIMED TO EVALUATE IF MBPC CAN BE USED IN PREDICTION OF EARLY BIRTH. TAKING THE FIRST TRIMESTER FROM PREGNANCY WAS STORED UNTIL THE TIMING OF DELIVERY.THE PARTICIPANTS WERE SEPARATED INTO TWO GROUPS ACCORDING TO THE TIME OF BIRTH, EARLY AND TIMELY. SERUM MBPC LEVELS BETWEEN TWO GROUPS EVALUATED.

NCT ID: NCT05509621 Completed - Nursing Caries Clinical Trials

The Effect of Positions on Physiological Parameters of Preterm Neonates Receiving Mechanical Ventilation

Start date: September 1, 2022
Phase: N/A
Study type: Interventional

This study was planned as an experimental study with a randomized crossover design to determine the effect of supine, prone, right lateral, left lateral, and quarter prone positions used during daily routine care in the neonatal intensive care unit on physiological parameters (oxygen saturation, heart rate, respiratory rate) of preterm neonates receiving mechanical ventilation.

NCT ID: NCT05453734 Completed - Preterm Clinical Trials

The Effect of Progressive Muscle Relaxation Exercises

Start date: November 20, 2018
Phase: N/A
Study type: Interventional

Purpose This study was carried out to examine the effectiveness of Progressive Muscle Relaxation (PMR) exercises on mothers' breastfeeding self-efficacy and depression level with preterm infants. Methods This study was conducted in a randomized controlled experimental design. The sample of the study consisted of 70 mothers with 32-36 weeks preterm infants (35/35 in experimental/control group) and hospitalized in the Neonatal Intensive Care Unit (NICU) of the university hospital in which the study was conducted. Introductory information form; Breastfeeding Self-Efficacy Scale (BSES), Edinburgh Postpartum Depression Scale (EPDS), and patient follow-up form were used to collect data. Progressive Muscle Relaxation (PMR) exercises were practiced on the mothers in the experimental group. The mothers were given training and instructions about the exercises. They were applied in the morning and evening for 2 weeks by the instructions. The BSES and EPDS score of both groups were evaluated in the 1st and 2nd-week follow-up.

NCT ID: NCT05438680 Completed - Preterm Clinical Trials

Bovine Colostrum in Prevention of Sepsis and Retinopathy of Prematurity

Start date: June 20, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate efficacy of bovine colostrum administration as a prophylaxis to decrease the incidence and the occurrence of retinopathy of prematurity in preterm neonates of gestational age less than 32 weeks during their hospital stay.

NCT ID: NCT05430100 Completed - Pain Clinical Trials

Reducing Pain During Orogastric Tube Placement in Preterm

Start date: July 10, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to determine the effectiveness of 3 different methods (breast milk pacifier, sucrose pacifier and pacifier) in reducing pain caused by Orogastric Tube (OGT) insertion in preterm newborns by monitoring behavioral and physiological changes in infants. The study was planned as a randomized controlled experimental study.

NCT ID: NCT05393817 Completed - Caffeine Clinical Trials

Caffeine Citrate Use and Electronic Activity of the Diaphragm (EDI) Changes

Start date: June 8, 2022
Phase:
Study type: Observational

Caffeine citrate, the first-line agent for apnea of prematurity, enhances diaphragmatic activity. EDI values of neurally adjusted ventilatory assist (NAVA) modes can be used to quantify the diaphragmatic activity triggered by electrical impulse from the respiratory center. This study aims to evaluate the EDI changes following caffeine citrate administration and cessation in preterm infants, and whether such changes are affected by different doses used variably in clinical settings.

NCT ID: NCT05359809 Completed - Stress Clinical Trials

Peripheral Intravenous Central Catheter Intervention in Preterm Infants

Start date: May 1, 2022
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate the effect of grasping reflex stimulation applied during peripheral intravenous central catheter (PIC) intervention on pain and stress in preterm infants receiving treatment and care in the neonatal intensive care unit.

NCT ID: NCT05333575 Completed - Preterm Clinical Trials

Lullaby and Classic Music's Effect on Vital Findings and Comfort

Start date: December 2, 2020
Phase: N/A
Study type: Interventional

In the study, lullabies and classical music played to preterm babies during orogastric tube feeding; It will be tried to determine the effect on cerebral oxygenation level, vital signs and comfort levels.

NCT ID: NCT05261503 Completed - Preterm Clinical Trials

Investigation of the Effectiveness of Environmental Enrichment-Based Intervention in Preterm Infants

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

The aim of this study is to investigate the effectiveness the HEP (Homeostasis-Enrichment-Plasticity) approach, which based upon the principles of enriched environment (EE) and ecological theories of development on preterm infants with developmental delay risk. Thirty-two preterm infants aged 4-10 months will be randomly divided into 2 groups as the HEP intervention group and the Traditional Physical Therapy (TPT) group. EE-based intervention will be applied to the HEP intervention group, and traditional physiotherapy will be applied to the TPT group for 12 weeks (24 sessions). The demographic information of the participants will be recorded. The motor and sensory functions of the infants will be evaluated with, the Peabody Developmental Motor Scales (PDMS-2) and the Test of Sensory Functions in Infants™ (TSFI™), respectively. Additionally, the anxiety status of the parents will be evaluated with the Beck Anxiety Inventory (BAI). All evaluations will be done twice, at the end and at the beginning of 12 weeks.