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Premature Birth clinical trials

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NCT ID: NCT02782650 Completed - Premature Birth Clinical Trials

Prenatal Counseling in Extreme Prematurity: Professionals' View

PreCo-profs
Start date: July 2012
Phase: N/A
Study type: Observational

This study is part of the PreCo study, evaluating Dutch care in (imminent) extreme preterm birth including current and preferred counseling, barriers and facilitators for preferred counseling from both obstetricians and neonatologists, as well as parents' views on this. Since 2010, intensive care can be offered in the Netherlands at 24+0 weeks gestation (with parental consent) but as some international guidelines, the Dutch guideline lacks detailed recommendations on organization, content and preferred decision-making of the counseling.

NCT ID: NCT02782637 Completed - Complications Clinical Trials

Prenatal Counseling in Extreme Prematurity: Parents' View

PreCo-parents
Start date: March 2015
Phase: N/A
Study type: Observational

This study is part of the PreCo study, evaluating Dutch care in (imminent) extreme preterm birth including current and preferred counseling, barriers and facilitators for preferred counseling from both obstetricians and neonatologists, as well as parents' views on this. Since 2010, intensive care can be offered in the Netherlands at 24+0 weeks gestation (with parental consent) but as some international guidelines, the Dutch guideline lacks detailed recommendations on organization, content and preferred decision-making of the counselling.

NCT ID: NCT02782559 Withdrawn - Clinical trials for Preterm Preeclampsia

Efficacy of Sildenafil in Preterm Preeclampsia

SIL
Start date: July 2016
Phase: Phase 2/Phase 3
Study type: Interventional

Randomized controlled trial to assess efficacy of Sildenafil in addition to expectant management for the treatment of preterm preeclampsia

NCT ID: NCT02781168 Active, not recruiting - Premature Newborn Clinical Trials

Influence of the Use of Hearing Protection in the Salivary Cortisol Level and in the Sleep of Premature Infants

Start date: June 2013
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the influence of the use of headphones in salivary cortisol levels in newborns (NB) during periods of nap aimed at noise reduction, brightness and handling NB, measure the concentrations of salivary cortisol before (baseline) and after the use of hearing protection (response) in the neonatal intensive care unit (NICU). A NICU nap periods and compare the influence of the use and non-use of hearing protection in salivary cortisol levels and sleep patterns of infants during nap periods of the NICU.

NCT ID: NCT02780791 Terminated - Infertility Clinical Trials

Maturation of Follicles After Transplantation of Ovarian Tissue Into the Pelvic Wall and the Ovary

Ovartrans
Start date: September 10, 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether the pelvic wall or the ovary represents a better location for the maturation of follicles in the context of ovarian transplantation after cryopreservation of ovarian tissue before cytotoxic therapies.

NCT ID: NCT02779374 Terminated - Clinical trials for Premature Ovarian Failure

Autologous Bone Marrow Transplantation for Premature Ovarian Insufficiency

BMT-POI
Start date: July 2016
Phase: N/A
Study type: Interventional

Currently, There is no treatment for Premature ovarian insufficiency (POI). Very small embryonic-like stem cells (VSELs) are found in the ovary. VSELs are able to regenerate the affected ovary. Stimulation was achieved by injection of mesenchymal stem cells that is supposed to secrete trophic factors. Numerous studies in mice have proved the efficacy of bone marrow transplantation (BMT) in resuming the ovarian function after chemotherapy-induced ovarian insufficiency. Allogeneic BMT raised the moral conflict about the origin of the newly developed oocytes. Several small studies examined the use of autologous BMT both in animal and in human. The results of these studies were promising. Intravenous injection is simpler and less invasive than ovarian injection as the later involves the use of laparoscopy. However, intravenous injection has not tested until now.

NCT ID: NCT02776332 Active, not recruiting - Clinical trials for Breast Milk Expression

The Merit Study (Manual Expression pRemature InfanTs)

MERIT
Start date: May 26, 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how the duration of manual expression affects milk volumes and levels of breastfeeding self-efficacy in mothers of premature infants. The specific aims of this study are to determine if the duration of manual expression in mothers of premature infants will result in: (a) an increase in breastfeeding self-efficacy (b) a difference in milk volume and (c) a correlation between breastfeeding self-efficacy and milk volume.

NCT ID: NCT02772835 Completed - Preterm Birth Clinical Trials

nHFOV vs nCPAP: Effects on Gas Exchange for the Treatment of Neonates Recovering From RDS

Start date: January 2016
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effects of two different techniques of non-invasive ventilation (nCPAP and nHFOV) on gas exchange in preterm infants recovering from respiratory distress syndrome.

NCT ID: NCT02770976 Completed - Preterm Infants Clinical Trials

Respiratory Pattern During Neurally Adjusted Ventilator Assist (NAVA) in Preterm Infants

Start date: May 2016
Phase: N/A
Study type: Interventional

This study is to investigate the effect of a wide range of assistance levels on respiratory pattern, breathing variability including tidal volume and peak inspiratory pressure during neurally adjusted ventilatory assist (NAVA) in preterm infants. The investigators also aim to explore whether the effects of NAVA on the electrical activity of diaphragm (Edi) signal amplitude, work of breathing and comfort of preterm infants.

NCT ID: NCT02770456 Completed - Premature Birth Clinical Trials

Fish Oil Supplementation to Pregnant Women in China

FOPCHIN
Start date: March 2008
Phase: N/A
Study type: Interventional

This randomized controlled trial with fish oil supplementation to pregnant women conducted in areas of China, which are generally low in fish intake and low income, aims at answering the following primary questions: - Is a dose of 2.0 g/d long chain n-3 fatty acids efficient in preventing preterm birth - Is a dose of 0.5 g/d long chain n-3 fatty acids efficient in preventing preterm birth - Is a dose of 0.5 g/d as efficient as a dose of 2.0 g/d in affecting timing of spontaneous delivery in the preterm period