Influence of Preconceptional Obesity on the Myometrial Cells Differentiation Toward a Contractyl Phenotype — ObeDi

Pregnancy Complication Clinical Trial

Official title:
Study of Role of Mononuclear Cells of Maternal Peripheric Blood in Human Myometrial Primar Cell Lines Differentiation Toward a Contratyl Phenotype: Influence of Preconceptional Obesity

Status Completed

Clinical Trial Summary

The purpose of this study is to improve the understanding of cellular mecanism involved in delivery disorders in obese women, first by characterizing the hyperplasia phenomenon of myometrail cells induced by inflammatory stimulation (Il-1B), then by studying the role of blood mononuclear cells, of leptine and of obese women sera to interfere with the transition of myometrial cells toward hyperplasia phenotype.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01762683
Study type	Interventional
Source	Centre Hospitalier Universitaire Dijon
Contact
Status	Completed
Phase	N/A
Start date	April 6, 2012
Completion date	January 15, 2016

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