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NCT05759442 Clinical Trial

Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics

PreDiabetes Clinical Trial

— BUHSCK  

Official title:
Clinical Efficacy and Safety of Metformin Versus Apple Cider Vinegar (ACV) in Prediabetics

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05759442
Other study ID # ERC 123/2022
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date January 1, 2023
Est. completion date July 15, 2023

Study information
Verified date August 2023
Source Bahria University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The goal of this clinical trial is to compare efficacy and safety of metformin versus apple cider vinegar in prediabetics . The main question[s] it aims to answer are: - Efficacy of metformin versus apple cider vinegar in prediabetics - Safety of metformin versus apple cider vinegar in prediabetics Researchers will compare group of prediabetics taking metformin with group of prediabetics taking apple cider vinegar to see if there is difference in safety and efficacy..

Recruitment information / eligibility
Status Completed
Enrollment 46
Est. completion date July 15, 2023
Est. primary completion date April 1, 2023
Accepts healthy volunteers No
Gender All
Age group 17 Years to 40 Years
Eligibility Inclusion Criteria: - Males and Female - 17-40 years age - Body Mass index (BMI) overweight and obese - FBS (100-125 mg/dl) - HBA1c 5.7% to 6.4% Exclusion Criteria: - Concomitant medical problems as established diabetes, hepatic or renal insufficiencies etc. - Known allergy or intolerance to metformin or apple cider vinegar

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Metformin Hydrochloride (HCL)
Tab Metformin HCL 500mg twice per day aimed at improving glycemic indices in Prediabetics
Dietary Supplement:
• Apple cider vinegar
Apple cider vinegar aimed at improving glycemic indices in Prediabetics

Locations
Country Name City State
Pakistan Diabetologist Clinics (02) Karachi

Sponsors (1)
Lead Sponsor Collaborator
Bahria University

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary Glycated Hemoglobin Change in glycosylated hemoglobin (HbA1c ) in percent 12 weeks
Primary Fasting Blood Sugar Change in fasting blood sugar (FBS) in mg/dL 12 weeks
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