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Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study

Posttraumatic Stress Disorder Clinical Trial

Official title:
Multi-modality Magnetic Resonance Imaging Biomarkers of Mild Traumatic Brain Injury: a Longitudinal Cohort Study

Clinical Trial Summary

This longitudinal cohort study aims to detect the topographical nature of the white matter microstructure and resting state functional connectivity patterns across the whole brain in the evolution of pathology as a function of time following mild TBI. All consecutively patients with the non-contrast head CT because of acute head trauma from the local emergency department (ED) formed the initial population of this study. Age, sex, education-level matched healthy controls will also be enrolled. The initial scan will performed within 7 days post-injury. Clinical assessment was performed within 24 hours of MR imaging and included a broad neuropsychological and symptom assessments. Follow-up examination will conduct at 1 month, 3 month, 6-12 months.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02868684
Study type Observational
Source First Affiliated Hospital Xi'an Jiaotong University
Contact
Status Completed
Phase
Start date August 2016
Completion date September 2020
View Details
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