Effects of Dairy- and Berry-based Snacks on Postprandial Glucose Metabolism in Older People

Postprandial Hyperglycemia Clinical Trial

— MAVIRE2  

Official title:

Tailored Food Solutions for Improving Nutrition and Well-being in Older People: Effects on Postprandial Responses

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04175353
• Other study ID #: MAVIRE2 247124
• Secondary ID: 4249/31/2014
• Status: Completed
• Phase: N/A
• Start date: February 1, 2016
• Est. completion date: December 31, 2016

Study information

• Verified date: November 2019
• Source: University of Eastern Finland
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Malnutrition or its risk is common among older people. To maintain adequate nutrition, increased meal frequency is important. In addition to main meals, regular consumption of nutrient- and energy-dense snacks is recommended. The study examines the post-meal responses to dairy- and berry-based snacks tailored for older people. The plasma concentrations of glucose, insulin and free fatty acids are measured during three hours after snack consumption. In addition, subjective satiety responses and heart rate variability are recorded.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 26
• Est. completion date: December 31, 2016
• Est. primary completion date: June 2, 2016
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Home-dwelling

Exclusion Criteria:

• Smoking

• Type 1 diabetes

• Type 2 diabetes treated with oral medications or insulin

• Cognitive impairment

• Antibiotic medication within the past 3 months

• Blood donation within the past month

Related Conditions & MeSH terms

• Hyperglycemia
• Postprandial Hyperglycemia

Intervention

Dietary Supplement:
• Dairy snack
The effects of dairy snack are compared with orange juice.
• Berry snack
The effects of two berry snacks are compared with berry soup.

Locations

Country	Name	City	State
Finland	University of Eastern Finland	Kuopio

Sponsors (1)

Lead Sponsor	Collaborator
University of Eastern Finland

Country where clinical trial is conducted

Finland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in postprandial glucose	Changes in plasma glucose concentration within 3 hrs after meal	3 hrs
Primary	Change in postprandial insulin	Changes in plasma insulin concentration within 3 hrs after meal	3 hrs
Secondary	Change in postprandial free fatty acids	Changes in plasma free fatty acid concentration within 3 hrs after meal	3 hrs
Secondary	Change in postprandial satiety scores assessed by using visual analogy scales	Visual analogue scales (VAS) are used to assess satiety and other related subjective sensations (fullness, hunger, desire to eat, alertness) within 3 hrs after meal. Each VAS consists of a 100-mm horizontal line anchored with verbal descriptions at each end expressing the weakest (0 mm) or strongest (100 mm) statement of sensation. Results are scores between 0 and 100.	3 hrs
Secondary	Heart rate variability	Electrocardiography monitoring for assessment of several variables of heart rate variability	3 hrs