Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis

Postoperative Pain Clinical Trial

Official title:

Effects of Photobiomodulation on Postoperative Pain After Primary Endodontic Therapy in Molars With Symptomatic Apical Periodontitis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05032612
• Other study ID #: HSC-DB-21-0579
• Status: Completed
• Phase: N/A
• Start date: September 16, 2021
• Est. completion date: March 16, 2022

Study information

• Verified date: March 2023
• Source: The University of Texas Health Science Center, Houston
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate the effects of photobiomodulation (PBM) on postoperative pain after endodontic treatment in mandibular molar teeth diagnosed with symptomatic apical periodontitis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 32
• Est. completion date: March 16, 2022
• Est. primary completion date: March 16, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Posterior mandibular molars

• No previous root canal therapy on the tooth in question

• Able to complete the endodontic treatment in one visit

Exclusion Criteria:

• Maxillary teeth, mandibular anteriors and premolars

• Infection (swelling, sinus tract) on the tooth in question

• Periodontal disease on the tooth in question

• Dental trauma

• Crown/ root fractures

• Systemic diseases

• Immunocompromised patients

Related Conditions & MeSH terms

• Pain, Postoperative
• Periapical Periodontitis
• Periodontitis
• Postoperative Pain

Intervention

Device:
• PBM Therapy
After the endodontic treatment, PBM therapy will be performed using a 660 nm diode laser (SiroLaser Advance Plus, Dentsply Sirona Inc, Charlotte, NC, USA), with an 8mm tip diameter.The laser tip will be placed on the following external surfaces in a contact mode: mesiobuccal, distobuccal, mesiolingual and distolingual . The power output of the laser will be 50mW and will be verified by Power Meter (PM600 Power/Energy meter, Molectron Detector Inc, Portland, OR, USA). Each site will be irradiated for 25 s with an energy density of 10 J/cm2 .
• PBM Sham
For the PBM sham similar procedure as PBM therapy will be performed without activating the laser.

Locations

Country	Name	City	State
United States	The University of Texas Health Science Center at Houston	Houston	Texas

Sponsors (1)

Lead Sponsor	Collaborator
The University of Texas Health Science Center, Houston

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Pain as Assessed by the Visual Analog Scale	This scale ranges form 0(no pain) to 10(worst pain)	72 hours after treatment
Secondary	Pain as Assessed by the Visual Analog Scale	This scale ranges form 0(no pain) to 10(worst pain)	0 hours, 6 hours, 12 hours and 24 hours hours after treatment