Effects of Methylprednisolone After Total Hip Arthroplasty

Status Completed

Clinical Trial Summary

The purpose of the study is to compare the effects of pre-operative methylprednisolone (125mg iv) versus placebo on postoperative outcome after hip arthroplasty.

The hypothesis is that pre-operative methylprednisolone (125mg iv) will reduce time to fulfill discharge criteria.

Clinical Trial Description

In spite of being one of the last century's most successful surgical procedures in treatment of advanced osteoarthritis total hip arthroplasty is still associated with postoperative pain and delayed rehabilitation. The investigators therefore decided to evaluate the effects of pre-operative methylprednisolone (125mg iv) versus placebo on postoperative outcome in a well defined fast-track setup after hip arthroplasty. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00968903
Study type	Interventional
Source	Hvidovre University Hospital
Contact
Status	Completed
Phase	Phase 4
Start date	April 2010
Completion date	January 2011

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04633850` - Implementation of Adjuvants in Intercostal Nerve Blockades for Thoracoscopic Surgery in Pulmonary Cancer Patients
Recruiting	`NCT03181620` - Sedation Administration Timing: Intermittent Dosing Reduces Time to Extubation	N/A
Completed	`NCT04579354` - Virtual Reality (VR) Tour to Reduce Preoperative Anxiety Before Anaesthesia	N/A
Recruiting	`NCT06007378` - Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery	N/A
Recruiting	`NCT05943015` - Analgesic Efficacy of Quadratus Lumborum, Paravertebral Blocks	N/A
Completed	`NCT04544228` - Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy	N/A
Completed	`NCT03678168` - A Comparison Between Conventional Throat Packs and Pharyngeal Placement of Tampons in Rhinology Surgeries	N/A
Completed	`NCT03286543` - Electrical Stimulation for the Treatment of Pain Following Total Knee Arthroplasty Using the SPRINT Beta System	N/A
Completed	`NCT03663478` - Continuous TQL Block for Elective Cesarean Section	Phase 4
Completed	`NCT04176822` - Designing Animated Movie for Preoperative Period	N/A
Completed	`NCT05170477` - Influence of Apical Patency Concept Upon Postoperative Pain After Root Canal Treatment	N/A
Not yet recruiting	`NCT04561856` - Fascia Iliaca Block Supplemented With Perineural Vs Intravenous Dexamethasone	Phase 4
Completed	`NCT06425601` - A Comparison of Silicone Versus Polyvinylchloride (PVC) Drains Following VATS Lobectomy	N/A
Completed	`NCT03612947` - TAP Block in Laparoscopic Cholecystectomy.	Phase 2
Completed	`NCT05974501` - Pre vs Post Block in Total Knee Arthroplasty (TKA)	Phase 4
Completed	`NCT05995912` - Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain	Phase 2
Completed	`NCT04571515` - Dose-Response Study of MR-107A-01 in The Treatment of Post-Surgical Dental Pain	Phase 2
Active, not recruiting	`NCT04190355` - The Effect of Irrigant Types Used During Endodontic Treatment on Postoperative Pain	N/A
Recruiting	`NCT05145153` - Incidence of Chronic Pain After Thoracic Surgery
Recruiting	`NCT03697278` - Monitoring Postoperative Patient-controlled Analgesia (PCA)	N/A