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The Effect of Esketamine on Postoperative Pain Relief in Patients Undergoing Laparoscopic Surgery

Postoperative Pain Clinical Trial

Official title:
The Effect of Low-dose Ketamine on Postoperative Pain Relief and Sleep Quality in Patients Undergoing Laparoscopic Uterine Surgery

Clinical Trial Summary

The purpose of this study is to investigate whether continuous intraoperative infusion of esketamine combined with the addition of esketamine to postoperative PCIA can improve postoperative pain and sleep quality in patients undergoing laparoscopic uterine surgery under general anesthesia.

Clinical Trial Description

Esketamine is the right isomer of ketamine, which is better than the original ketamine and has fewer side effects. In addition, for some gynecological hysterectomy patients who have poor sleep quality and anxiety after surgery, Esketamine also has the effect of treating depression. Due to the side effects of postoperative nausea, vomiting and hyperalgesia caused by excessive dosage of some opioids, this study will continue to inject small doses of esketamine during the operation to reduce the intraoperative dosage of opioids, and add esketamine to the postoperative PCIA for analgesia. To explore whether this method can reduce the incidence of moderate and severe postoperative pain in patients with laparoscopic uterine surgery under general anesthesia. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06300944
Study type Interventional
Source General Hospital of Ningxia Medical University
Contact Ma Hanxiang
Phone 86-13519591508
Email mahanxiang@hotmail.com
Status Recruiting
Phase N/A
Start date December 1, 2023
Completion date October 1, 2024
View Details
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