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Postoperative Pain clinical trials

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NCT ID: NCT04003688 Completed - Obesity Clinical Trials

Magnesium Sulfate Dose in Obese Patients.

Start date: August 26, 2019
Phase: N/A
Study type: Interventional

Magnesium sulfate has been applied in various situations due to actual or potential benefits related to neuroprotection, treatment of eclampsia/pre-eclampsia, arterial hypertension, adrenergic reflex under laryngoscopy/intubation and, shivering, nausea and vomiting, among others. In anesthesia it has been useful as an analgesic adjuvant; however, the method to calculate the dose of magnesium sulfate in obese population is unclear. The objective of this project is to compare two methods of dose calculation based either on the real weight or corrected ideal weight.

NCT ID: NCT04000100 Completed - Postoperative Pain Clinical Trials

Neostigmine for Ultrasound Guided Supraclavicular Brachial Plexus Block

Start date: July 15, 2018
Phase: N/A
Study type: Interventional

Patients were randomly allocated into Two equal study groups each contain (40) patients : Patients in Group A received supraclavicular block using 25mL of 0. 5% bupivacaine and 1 mL normal saline and patients in Group B received 25 mL 0. 5% bupivacaine and 1 mL neostigmine (0.5 mg). The investigators found that neostigmine when used as an adjuvant to bupivacaine in ultrasound guided supraclavicular brachial plexus block has advantage over bupivacaine alone especially in the quality of sensory block and provide safe and effective post-operative analgesia in patients undergoing forearm surgeries

NCT ID: NCT03989570 Completed - Postoperative Pain Clinical Trials

Transversus Abdominis Plane Block Versus Erector Spinae Plane Block

Start date: May 15, 2019
Phase: N/A
Study type: Interventional

The TAP block, first described by Rafi in 2001, is comprised of deposition of a local anesthetic into the anatomical plane between the internal oblique and transverses abdominis muscles, where thess thoracoabdominal nerves (T6-L1) contribute to the main sensory supply of the skin, muscles, and parietal peritoneum of the anterior abdominal wall. These nerves branch and communicate extensively with each other in the TAP . Erector spinae plane (ESP) block is a recently described interfascial block in which the local anaesthectic is placed over or below the plane of the erector spinae muscle, near where the spinal nerves come out from the spine before they start to divide. Some publications have shown its effectiveness in treating thoracic and abdominal postoperative pain. Postoperative pain is the major obstacle for early postoperative ambulation and increases the risk of venous thromboembolism, respiratory complications and prolongs the hospital stay. Parietal pain is the chief component of postoperative pain after abdominal surgeries. Large doses of opioids are required to mitigate this pain, but they are poorly tolerated. Multimodal analgesia is effective in handling postoperative pain and in attenuating the side effects of large doses of a single analgesic .

NCT ID: NCT03979105 Completed - Pain Clinical Trials

Cardiovascular Safety After Continuous Ketamine Infusion

Start date: July 1, 2017
Phase:
Study type: Observational

Observational study that evaluate the cardiovascular and neuropsychiatric side effects of ketamine analgesic infusions for acute pain

NCT ID: NCT03968523 Completed - Postoperative Pain Clinical Trials

Loco/Regional Anaesthesia Evaluation in Laparoscopic Hernioplasty

Start date: April 23, 2019
Phase: N/A
Study type: Interventional

Laparoscopic hernioplasty is associated with lesser postoperative pain and quick return to work. TAP block is the gold standard technique in this type of hernioplasty. Our aim is to compare TAP block with a novel local infiltration technique that uses direct laparoscopical vision.

NCT ID: NCT03968497 Completed - Postoperative Pain Clinical Trials

Impact of Gender on Perceived Postoperative Pain

G-PAIN
Start date: September 11, 2018
Phase: N/A
Study type: Interventional

Postoperative pain is a common problem after surgical procedures with many patients afflicted worldwide. Fundamental challenges are the complexity of measuring pain appropriately, and the many associated possible confounders. Over the last decades, gender of the investigator has been identified as a conceivable bias in the assessment and management of pain in experimental, as well as, clinical research. However, to the investigators knowledge this issue has not so far been systematically investigated in a postoperative setting. The objective of this study was to investigate whether the gender of the investigator has an impact on the reported levels of pain intensity after acute or scheduled surgery. In this prospective paired cross-over study, two investigators of opposite gender independently obtained individually reported pain intensity levels in each study patient based on three different methods of pain assessment the Visual Analogue Scale (VAS), the Numeric Rating Scale (NRS), and the Painmatcher® (PM) technique based on electrical stimulation, in a postoperative study setting at a large urban university hospital in southern Sweden.

NCT ID: NCT03967847 Completed - Postoperative Pain Clinical Trials

Oral Ketorolac for Arthroscopic Rotator Cuff Repair

Start date: February 11, 2019
Phase: Phase 3
Study type: Interventional

1. The investigators aim to examine the use of IV and oral ketorolac as an adjunctive agent to the standard of care pain protocol for postoperative pain control following arthroscopic rotator cuff repair. 2. The investigators hypothesize that the use of IV and oral ketorolac in addition to the standard of care pain protocol will reduce postoperative opioid consumption following arthroscopic rotator cuff repair.

NCT ID: NCT03967171 Completed - Postoperative Pain Clinical Trials

The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section

NCT ID: NCT03944759 Completed - Postoperative Pain Clinical Trials

Efficacy of Serratus Anterior Plane Block Mastectomy

Start date: May 7, 2019
Phase: N/A
Study type: Interventional

Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .

NCT ID: NCT03942107 Completed - Postoperative Pain Clinical Trials

Postoperative Pain After Dental Post Application

Start date: April 5, 2019
Phase: N/A
Study type: Interventional

In this study the effect of dental post application on postoperative dental pain in patients with asymptomatic teeth after a single-appointment root canal treatment will be evaluated.