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Postoperative Infection clinical trials

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NCT ID: NCT06044428 Recruiting - Pneumonia Clinical Trials

Steadysense -Early Detection of Postoperative Infections Through Continuous Temperature Measurement

Start date: August 14, 2023
Phase:
Study type: Observational

The goal of this observational study is to review whether postoperative infections can be detected earlier by a continuous measurement of body temperature of patients compared to single daily measurements. Within 25 weeks 100 patients, which underwent visceral surgery less than 48h ago, will be included. A patch (Steadytemp ®) will be attached to participants, continuously measuring the body temperature. In addition infection parameters and medication of the participants will be documented.

NCT ID: NCT05961930 Recruiting - Clinical trials for Postoperative Infection

Surgeon's Performance in Predicting Postoperative Infections

SPIRIT
Start date: February 1, 2023
Phase:
Study type: Observational

Post-surgical (bacterial) infections are the most frequent post-surgical complications, including deep or superficial wound infections, urinary tract infections, pneumonia, and even sepsis. Approximately 6.5-25% of all surgical patients will develop any type of bacterial infection. To personalize surgical infection management, (Artificial Intelligence) models are in the making to predict which patients are at high or low risk of developing a post-surgical infection. In order to benchmark these prediction models to the predictive capabilities of surgeons, the investigators aim to investigate the performance of surgeons in predicting the risk of a patient developing (any type) of post-surgical infection within 30 days.

NCT ID: NCT05052619 Recruiting - Antibiotics Clinical Trials

Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes

Start date: July 1, 2021
Phase: N/A
Study type: Interventional

Intra-abdominal infection is one of the most serious complications after pancreatic resection. The preventive use of antibiotics intraoperatively could reduce the incidence rate of postoperative intra-abdominal infection. According to the previous retrospective study, changes of serum lactate level on postoperative day1 could predict the incidence rate of postoperative intra-abdominal infection. This prospective RCT is to further validate and promote the findings and conclusion.

NCT ID: NCT05021315 Recruiting - Clinical trials for Cesarean Section Complications

Vaginal Cleaning Using Povidone Iodine Before CS to Reduce Postoperative Wound Infection

Start date: September 15, 2021
Phase: Phase 3
Study type: Interventional

The aim of work to assess the effectiveness of preoperative vaginal cleansing with povidone iodine on reduction of post caesarean section wound infection Research questions: Does vaginal cleaning using povidone iodine before cesarean section has effect on reduction of postoperative wound infection??

NCT ID: NCT03903354 Recruiting - Clinical trials for Postoperative Infection

Intraoperative Hyperglycemia and Infections After Orthopedic Surgery

Start date: January 13, 2018
Phase:
Study type: Observational [Patient Registry]

Postoperative infections are a common complication. A relationship between perioperative severe hyperglycemia and postoperative infections has been found in patients undergoing craniotomy. The aim of this study is to evaluate the epidemiology of intraoperative severe hyperglycemia (BGC >180 mg/dL; 10 mmol/L) and postoperative infections (wound, urinary and prosthetic joint infection) and to investigate if severe intraoperative hyperglycemia is associated with an higher risk of early postoperative (within the 7th postoperative days) infections (wound, urinary and prosthetic joint infection).

NCT ID: NCT01838733 Recruiting - Clinical trials for Myocardial Infarction

Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery

Start date: April 2014
Phase: N/A
Study type: Observational

Cerebral desaturations occur frequently in patients undergoing non-cardiac surgery. The definition of what constitutes a cerebral desaturation, the incidence of the phenomenon, the association between desaturations and perioperative outcome, and the mechanistic explanations of cerebral desaturations remain unexamined. This study seeks to identify the true incidence and magnitude of cerebral desaturations in high-risk non-cardiac surgical patients and the association between desaturations and perioperative outcome. The investigators will attempt to determine the following (1) The proper definition, incidence and severity of decreased cerebral saturation (rSO2) in high-risk non-cardiac surgical patients (2) the mechanisms surrounding decreases in rSO2 by correlating it with alterations in physiologic parameters (such as blood pressure, cardiac output, hemoglobin concentration, and carbon dioxide levels) and (3) to correlate the incidence and severity of decreased rSO2 with relevant perioperative. The investigators will also analyze a panel of inflammatory biomarkers to determine if these biomarkers have the ability to predict postoperative complications. The investigators will study 200 high-risk patients undergoing high-risk non-cardiac surgery. The investigators will determine the incidence and severity of decreases in rSO2, the associated factors with the occurrence of decreased rSO2, and the relationship between decreases in rSO2 and adverse perioperative outcome with a composite of well defined perioperative complications such as death, myocardial infarction, cerebrovascular accident, acute kidney injury, delirium, postoperative infections, and the need for mechanical ventilation.