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Postoperative Complications clinical trials

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NCT ID: NCT00511212 Withdrawn - Clinical trials for Postoperative Complications

Intravenous Immunoglobulin in Combination Therapy With Antibacterial Agents for SSI of the Lower Digestive Tract

Start date: August 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the clinical usefulness of IVIG in combination therapy with antibacterial agents for severe peritonitis after lower digestive tract surgery.

NCT ID: NCT00488904 Completed - Colorectal Cancer Clinical Trials

Omega-3 Fatty Acids and Postoperative Complications After Colorectal Surgery

omega3
Start date: June 2007
Phase: Phase 4
Study type: Interventional

To discover whether an Omega-3 fatty acid (eicosapentaenoic acid/EPA and docosahexaensyre/DHA) enriched nutritional supplement given 7 days preoperatively and 7 days postoperatively may reduce the frequency of postoperative infectious complications defined as: pneumonia, wound infection, urinary tract infection, peritonitis (including anastomotic leakage) and septic conditions of any cause in patients who undergo elective operations for colorectal cancer compared with a nutritional preparation that is identical apart from the EPA content.

NCT ID: NCT00478348 Completed - Clinical trials for Postoperative Complications

Should Prosthetic Repair of Incisional Abdominal Hernias be Drain or Not?

Start date: May 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether drainage after prosthetic repair of incisional abdominal hernias increases or decreases complications such as infection, seromas and hematomas.

NCT ID: NCT00457080 Completed - Clinical trials for Postoperative Complications

Application of Capnography Monitoring on the General Care Nursing Unit

ETCO2
Start date: October 2006
Phase: N/A
Study type: Interventional

The aim of this study is to increase the detection of undiagnosed obstructive sleep apnea (OSA) and secondly to increase the sensitivity for detection of respiratory depression (< 6 breaths per minute) in post operative patients on the general care nursing unit.

NCT ID: NCT00455182 Withdrawn - Pain Clinical Trials

Acupuncture for Pain Management After Hip or Knee Arthroplasty

Start date: March 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether patients treated with acupuncture post-operatively following knee or hip arthroplasty achieve better pain control as measured by the Visual Analog Scale and pain medication use.

NCT ID: NCT00426790 Recruiting - Clinical trials for Postoperative Complications

Open Lung Approach During General Anaesthesia to Prevent Post-Operative Pulmonary Complications

Start date: n/a
Phase: N/A
Study type: Interventional

The hypothesis of this study is that the "Open lung approach" ( recruitment and PEEP) during general anaesthesia reduces atelectasis formation and improves respiratory function in the immediate post-operative period after major abdominal surgery. This is a prospective, randomized, controlled clinical-trial,performed in patients undergoing major abdominal surgery, to compare the effects on the post-operative pulmonary complications of two different intraoperative ventilatory strategies during general anaesthesia: 1- Control Group: PEEP 0 cmH2O without recruitment manoeuvre; 2- Treatment Group:recruitment manoeuvre (after intubation and before extubation) and PEEP 10 cmH2O In the post-operative period the following variables will be recorded at the first, third and fifth postoperative day: 1- Gas-exchange in air; 2- Chest X-ray for atelectasis evaluation; 3- signs of pulmonary complication (cough, secretions, dyspnea, thoracic pain)

NCT ID: NCT00411970 Completed - Clinical trials for Postoperative Complications

20- Versus 23- Gauge System for Pars Plana Vitrectomy

Start date: September 2004
Phase: Phase 4
Study type: Interventional

The aim of the present study is to compare the functional and clinical differences and advantages between a standard operating system and a newly developed even smaller system for pars plana vitrectomy. The present study may work out the possible advantages and disadvantages between the routinely used 20-gauge vitrectomy system and the newly developed 23-gauge device.

NCT ID: NCT00410267 Terminated - Inflammation Clinical Trials

Trial Comparing Ketorolac Tromethamine 0.4% & Prednisolone Acetate 1% in Reducing Post-SLT Anterior Chamber Flare & Cells

Start date: February 2006
Phase: N/A
Study type: Observational

Selective laser trabeculoplasty (SLT) is a new alternative to anti-glaucoma medications for the treatment of primary open angle glaucoma. After SLT, many patients experience mild to moderate inflammation inside the eye - specifically in the front chamber of the eye (the part in front of the colored part of the eye). This mild front chamber reaction is typically treated with anti-inflammatory agents such as corticosteroids and nonsteroidal anti-inflammatory agents (NSAIDs). Some physicians do not use these agents as they feel they may interfere with the way the laser works to treat glaucoma. Topical (applied to the surface) corticosteroids can cause an increase in the pressure of the eye (intraocular pressure or IOP), cataract formation, or a possible increase in infection with long-term use. These side effects have not been reported to occur with NSAIDs, which are effective in controlling pain after SLT and reducing signs of inflammation such as irritation, swelling, tenderness, and soreness. This research study will compare an NSAID, ketorolac tromethamine 0.4% (Acular LS), with a corticosteroid, prednisolone acetate 1% (Pred Forte), and with a placebo, which contains no active medicine (Refresh Tears). Ketorolac tromethamine 0.4%, prednisolone acetate 1%, and Refresh Tears are all FDA (Food and Drug Administration) approved for use in inflammation after surgery.

NCT ID: NCT00395447 Completed - Clinical trials for Postoperative Complications

REPLACE: Implantable Cardiac Pulse Generator Replacement Registry

REPLACE
Start date: July 2007
Phase: Phase 4
Study type: Observational

The objective of this study is to prospectively estimate the all-cause complication rates at 6-months for patients undergoing generator replacement due to elective replacement indicator (ERI), advisory, or upgrade without a planned system modification or with a planned system modification. Secondarily, this study aims to compare the influence of baseline variables contributing to the all-cause complication rates for subjects undergoing generator replacement.

NCT ID: NCT00373919 Not yet recruiting - Clinical trials for Postoperative Complications

The Effect of Erythromycin on Occurrence of Leaks From Cervical Esophageal-Gastric Anastomosis After Trans-Hiatal Esophagectomy

Start date: n/a
Phase: N/A
Study type: Interventional

Cervical anastomotic leak is one of the most common complications after trans-hiatal esophagectomy. Hypothesis: An early post operative administration of a pro-kinetic dosage of erythromycin will reduce leak occurrence. Design: This is a prospective, randomized, double blind, placebo controlled study. Number of patients: 30. Inclusion Criteria: - Patients after trans-hiatal esophagectomy Exclusion Criteria: - Allergy to erythromycin - Use of phenothiazine - QT prolongation - Liver function test (LFT) abnormalities - Myasthenia gravis - Cardiomyopathy