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Postoperative Complications clinical trials

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NCT ID: NCT00918762 Completed - Clinical trials for Head and Neck Cancer

Transoral Robotic Surgery or Standard Surgery in Treating Patients With Benign or Malignant Tumors of the Larynx and Pharynx

Start date: May 2009
Phase: Phase 1
Study type: Interventional

RATIONALE: Transoral robotic surgery may make it easier to find and remove benign or malignant tumors of the larynx and pharynx and cause less damage to normal tissue. It is not yet known whether transoral robotic surgery is more effective than standard surgery in diagnosing and treating larynx and pharynx tumors. PURPOSE: This phase I trial is studying how well transoral robotic surgery works compared with standard surgery in treating patients with benign or malignant tumors of the larynx or pharynx.

NCT ID: NCT00859157 Completed - Breast Cancer Clinical Trials

Pain After Tumescent Mastectomy or Standard Mastectomy in Women With Stage I, Stage II, or Stage III Breast Cancer

Start date: October 2008
Phase: N/A
Study type: Observational

RATIONALE: New surgery techniques may lessen pain after breast surgery. It is not yet known whether tumescent mastectomy or standard mastectomy results in less pain in women with breast cancer. PURPOSE: This clinical trial is studying pain after tumescent mastectomy compared with pain after standard mastectomy in women with stage I, stage II, or stage III breast cancer.

NCT ID: NCT00830089 Completed - Clinical trials for Postoperative Complications

Trial of a Transversus Abdominis Plane (TAP) Block in Laparoscopic Colorectal Surgery

Start date: September 2009
Phase: N/A
Study type: Interventional

Keyhole surgery for bowel disease has brought great benefits, enabling patients to recover quicker from surgery and so return to normal activities. Although keyhole surgery reduces pain following abdominal surgery, it still causes enough pain to require strong pain killing medications such as morphine-like drugs which, although good pain killers, can have a detrimental effect on the recovery of bowel function, leading to feelings of nausea and vomiting and ultimately delaying recovery. These side-effects can reduce the potential benefits from keyhole surgery and our "fast-track" recovery programmes. The aim of this project is to assess the effectiveness of a new method of pain control after keyhole bowel surgery. The study involves the injection of local anaesthetic into the abdominal muscles once the patient is anaesthetised. Although use of local anaesthetic is common practice, we are looking at a new technique of injecting it called a transversus abdominis plane (or TAP) block. This technique will attempt to block the pain nerves to the abdomen prior to the operation beginning. We plan to investigate whether this new technique will reduce the amount of pain following keyhole bowel surgery. If successful, it might be used to further enhance people's recovery from bowel surgery.

NCT ID: NCT00797121 Recruiting - Surgery Clinical Trials

Preoperative Biliary Drainage for Resectable Hilar Cholangiocarcinoma

Start date: May 2008
Phase: Phase 4
Study type: Interventional

This study is to investigate whether preoperative biliary drainage can reduce the postoperative morbidity in patients with hilar cholangiocarcinoma.

NCT ID: NCT00789659 Withdrawn - Wound Infection Clinical Trials

Incisional Wound Vac in Obese Patients

Start date: December 2010
Phase: N/A
Study type: Interventional

It is the belief of the investigators that the current trends in complication rates associated with fixation of pelvic ring injuries and acetabular fractures in the obese are unacceptable. The overwhelming majority of these complications can be attributed to problems with surgical wound healing. The investigators feel that if a cost effective and easily performed intervention can be prospectively utilized in a specific at-risk orthopaedic trauma population in order to control a potentially devastating complication, then efforts in discovering such an intervention may prove valuable. It is our hypothesis that obese patients treated with V.A.C. therapy after standard closure of trauma-related, operative orthopaedic incisions will have fewer postoperative wound complications.

NCT ID: NCT00782704 Completed - Clinical trials for Postoperative Complications

Development and Validation of a Morbidity Index for Complications in Minor and Major Abdominal Surgery

Start date: October 2008
Phase: N/A
Study type: Observational

The aim is to develop and validate a morbidity index for postoperative complications in patients undergoing visceral surgery.

NCT ID: NCT00769821 Completed - Breast Cancer Clinical Trials

The Impact of Lymphedema on Breast Cancer Survivors

Start date: February 2007
Phase: N/A
Study type: Observational

RATIONALE: Gathering information from breast cancer survivors about lymphedema; its symptoms and their impact on shoulder, arm, and hand functioning; and quality of life may help doctors learn more about the disease. PURPOSE: This clinical trial is studying the impact of lymphedema on breast cancer survivors.

NCT ID: NCT00743236 Completed - Kidney Cancer Clinical Trials

Warm Ischemia or Cold Ischemia During Surgery in Treating Patients With Stage I Kidney Cancer

Start date: August 2008
Phase: N/A
Study type: Interventional

RATIONALE: Warm ischemia is the clamping of blood vessels without cooling the kidney. Cold ischemia is the clamping of blood vessels with kidney cooling. It is not yet known whether warm ischemia is more effective than cold ischemia in patients undergoing surgery for stage I kidney cancer. PURPOSE: This randomized phase III trial is studying warm ischemia to see how well it works compared with cold ischemia during surgery in treating patients with stage I kidney cancer.

NCT ID: NCT00736125 Completed - Clinical trials for Postoperative Complications

A Study to Determine if Carbon Dioxide Lavage During Total Knee Surgery Reduces Intraoperative Embolic Events

Start date: December 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to determine if the use of a carbon dioxide lavage device (CarboJet) to clean bone surfaces during total knee surgery decreases intraoperative embolic events when compared with standard orthopedic techniques.

NCT ID: NCT00726570 Terminated - Clinical trials for Postoperative Complications

Alterations of Blood Clotting With the Use of Sequential Compression Devices on the Lower Limbs

TEGLeg
Start date: August 2008
Phase: N/A
Study type: Interventional

This study aims to assess possible alteration in coagulation (blood clotting) following treatment with sequential compression devices (SCD) plus low-molecular weight heparin (LMWH) as opposed to LMWH alone. The investigators will examine coagulation in the early postoperative period of patients undergoing major abdominal surgery during their stay in our Intensive Care Unit. In addition to common laboratory tests, the investigators will examine coagulation using TEG®, a device which allows a semi-quantitative examination of all phases of coagulation.