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NCT03060070 Clinical Trial

Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block

Postoperative Analgesia Clinical Trial

Official title:
Comparison of the Analgesic Effect of Ketamine Versus Dexmedetomidine Added to Local Anesthetic in TAP Block for Lower Abdominal Cancer Surgery

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03060070
Other study ID # 321
Secondary ID
Status Completed
Phase Phase 2/Phase 3
First received February 17, 2017
Last updated July 1, 2017
Start date March 10, 2017
Est. completion date July 1, 2017

Study information
Verified date July 2017
Source Assiut University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Comparing the analgesic effects of ketamine and dexmedetomidine when added to local anesthetic in TAP block for postoperative analgesia after lower abdominal cancer surgery.

Recruitment information / eligibility
Status Completed
Enrollment 90
Est. completion date July 1, 2017
Est. primary completion date June 25, 2017
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria:

- All patients ASA I and II to whom abdominal surgery for cancer will be conducted will be included in the study

Exclusion Criteria:

- Coagulopathies

- ASA III or IV, patient refusal, sensitivity to the used drugs

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Ketamine
Ketamine at a dose of 0.5mg/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block
• dexmedetomidine
dexmedetomidine at a dose of 1ug/kg will be added to bupivacaine 0.25 (total volume 20ml) in each side using sonar guided TAP block
• control group
20ml of 0.25% bupivacaine will be injected in each side of the TAP block

Locations
Country Name City State
Egypt South Egypt Cancer Institute Assiut Assiut University

Sponsors (2)
Lead Sponsor Collaborator
Assiut University South Egypt Cancer Institute

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary postoperative rescue morphine consumption postoperative rescue morphine consumption 24 hours postoperative
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