Compare the Agility Exercise and Resistance Exercise on Physical Function and Stability in Osteoporotic Women

Postmenopausal Osteoporosis Clinical Trial

Official title:

Tainan Hospital, Ministry of Health and Welfare, Taiwan

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06457308
• Other study ID #: TainanHMHW
• Status: Completed
• Phase: N/A
• Start date: July 14, 2021
• Est. completion date: December 31, 2022

Study information

• Verified date: April 2024
• Source: Tainan Hospital, Ministry of Health and Welfare
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Osteoporosis weakens bones with age, increasing fracture risk. Exercise improves physical function and reduces falls, crucial for preventing osteoporotic fractures, especially with balance, resistance, and multi-component training. Agility exercise, integrating various aspects like aerobic, strength, balance, and cognitive tasks, is promising for fall prevention in older adults, though its effectiveness in osteoporosis is not extensively studied.

This study compares agility and resistance exercise impacts on physical function and balance stability in postmenopausal osteoporosis. Fifty-one women (average age: 68±6.3y, BMI: 22.3±2.7 kg/m2) were divided into agility exercise (AG), resistance exercise (RG), and control groups (CG) through purposive sampling. AG and RG received added intervention training once a week for 2 hours over 12 weeks. Main outcomes included physical function and balance stability measured through various tests.

Description:

Main activities of agility training group (AG): Use rope ladders and cones to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training.

Main activities of resistance training group (AG): Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 51
• Est. completion date: December 31, 2022
• Est. primary completion date: May 31, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 50 Years and older

Eligibility

Inclusion Criteria:

postmenopausal osteoporosis diagnosed with DXA( Hologic, W type, Caucasian reference, T-score?-2.5 in L-spine or hip)

Exclusion Criteria:

Unable to attend the training sessions due to physical problems Had joined previous exercise program

Related Conditions & MeSH terms

• Fall Prevention
• Osteoporosis
• Osteoporosis, Postmenopausal
• Physical Function
• Postmenopausal Osteoporosis

Intervention

Biological:
• Physical training of agility
A grouped training for older adults in the community. The training classed lasted for 12 weeks, one session a week for 120 mins, and are under instructed by a trained experienced sport instructor. Use rope ladders and cones to perform multiple tasks of direction changes, acceleration and deceleration of footsteps, hand and foot coordination and spatial orientation training,
• Physical training of resistance
A grouped training for older adults in the community. The training classed lasted for 12 weeks, one session a week for 120 mins, and are under instructed by a trained experienced sport instructor. Resistance training for upper and lower limb muscles and core muscles, including squats, use of elastic bands, and simple bars

Locations

Country	Name	City	State
Taiwan	Chen, Ying-Chen	Tainan

Sponsors (1)

Lead Sponsor	Collaborator
Tainan Hospital, Ministry of Health and Welfare

Country where clinical trial is conducted

Taiwan, 

References & Publications (4)

Donath L, van Dieen J, Faude O. Exercise-Based Fall Prevention in the Elderly: What About Agility? Sports Med. 2016 Feb;46(2):143-9. doi: 10.1007/s40279-015-0389-5. — View Citation

Lichtenstein E, Morat M, Roth R, Donath L, Faude O. Agility-based exercise training compared to traditional strength and balance training in older adults: a pilot randomized trial. PeerJ. 2020 Apr 14;8:e8781. doi: 10.7717/peerj.8781. eCollection 2020. — View Citation

Miko I, Szerb I, Szerb A, Bender T, Poor G. Effect of a balance-training programme on postural balance, aerobic capacity and frequency of falls in women with osteoporosis: A randomized controlled trial. J Rehabil Med. 2018 Jun 15;50(6):542-547. doi: 10.2340/16501977-2349. — View Citation

Morat M, Morat T, Zijlstra W, Donath L. Effects of multimodal agility-like exercise training compared to inactive controls and alternative training on physical performance in older adults: a systematic review and meta-analysis. Eur Rev Aging Phys Act. 2021 Feb 25;18(1):4. doi: 10.1186/s11556-021-00256-y. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Physical function of upper limb strength	arm curl in 30 secs	after the completed training course, about 12 weeks
Primary	Physical function of upper limbs strength	Hand grip	after the completed training course, about 12 weeks
Primary	Physical function of lower limbs	Walking speed	after the completed training course, about 12 weeks
Primary	Physical function of dynamic balance	Up and go test	after the completed training course, about 12 weeks
Primary	Physical function of lower limbs	Sit to stand in 30 secs	after the completed training course, about 12 weeks
Primary	Physical function of static balance	One leg stand test	after the completed training course, about 12 weeks
Primary	Stability index	Biodex balance system device	after the completed training course, about 12 weeks