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Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache

Postdural Puncture Headache Clinical Trial

Official title:
Addition of Pyridostigmine to Conventional Management of Postdural Puncture Headache

Clinical Trial Summary

Postdural puncture headache (PDPH) is a major complication of neuraxial anesthesia that can occur following spinal anesthesia and with inadvertent Dural puncture during epidural anesthesia. The presence of Pyridostigmine in CSF would be expected to increase the level of acetylcholine in CSF and subsequently in the brain through inhibition of cholinesterase. The increased level of acetylcholine would produce cerebral vasoconstriction.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05969119
Study type Interventional
Source Ain Shams University
Contact
Status Completed
Phase Phase 4
Start date July 25, 2023
Completion date January 3, 2024
View Details
See also
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