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Iloperidone for Symptoms of Arousal in Post Traumatic Stress Disorder (PTSD)

Post Traumatic Stress Disorder Clinical Trial

Official title:
A Double-Blind, Placebo-Controlled Random Order Crossover Study of Iloperidone for Symptoms of Arousal in PTSD Including Insomnia and Irritability.

Clinical Trial Summary

A Double-Blind Placebo-Controlled Random Order Crossover Pilot Study of Iloperidone for Symptoms of Arousal in PTSD.

Clinical Trial Description

During Period A, subjects will receive 8 weeks of iloperidone or placebo (2 weeks titration period followed by 6 weeks on stable dose). Then they will be reassessed for response during Period A; study drug will be discontinued and washed out over the following 2 weeks. They will then begin Period B on the alternate blinded treatment with similar titration and assessment, initially weekly and then every other week for a total of another 8 weeks. The purpose of the study is to determine whether Iloperidone is effective in the treatment of some symptoms in patients with PTSD, particularly difficulty falling or staying asleep, trauma dreams and daytime irritability or outbursts. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01917318
Study type Interventional
Source University of Colorado, Denver
Contact
Status Terminated
Phase Phase 2
Start date July 2013
Completion date February 2014
View Details
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