Post-Traumatic Stress Disorder Clinical Trial
Official title:
Effects of Early Psychological Intervention to Prevent PTSD
Verified date | September 2016 |
Source | Emory University |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Interventional |
This study will examine the use of prolonged exposure therapy on people who have recently experienced a trauma to prevent them from developing post-traumatic stress disorder.
Status | Completed |
Enrollment | 139 |
Est. completion date | January 2012 |
Est. primary completion date | January 2012 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years to 65 Years |
Eligibility |
Inclusion Criteria: - Presenting to the emergency department of Emory University School of Medicine/Grady Memorial Hospital for rape in the past 72 hours - Meets DSM-IV diagnostic criterion A in which both of the following are present: (i) The person experienced, witnessed, or was confronted with an event or events that involved actual or threatened death or serious injury or a threat to the physical integrity of self or others (ii) The person's response involved intense fear, helplessness, or horror - Speaks and understands spoken English - Can see the assessment forms, hear instructions, and function at an emotional and intellectual level sufficient to allow accurate completion of all assessment instruments - No significant traumatic injuries, as determined by the physician Exclusion Criteria: - Current or history of mania, schizophrenia, or other psychoses - Current (past month) prominent suicidal ideation or recent (past 3 months) parasuicidal behavior or other self-injurious behavior, such as low lethality cutting - Current (past month) substance dependence; people who meet criteria for current substance abuse but not dependence, or past dependence and have been in remission for at least 1 month are eligible. - Experienced a loss of consciousness for more than 5 minutes as a result of injuries sustained during the trauma - Intoxicated, altered, or highly distressed to the degree that accurate completion of the study assessments or participation in study procedures is not possible - Blood alcohol level above .08, determined by breathalyzer in the emergency department - Not alert, oriented, and coherent - In severe pain, active labor, or respiratory distress or hemodynamically compromised in any way |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Prevention
Country | Name | City | State |
---|---|---|---|
United States | Grady Memorial Hospital, Emergency Department | Atlanta | Georgia |
Lead Sponsor | Collaborator |
---|---|
Emory University | National Institute of Mental Health (NIMH) |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | PTSD Symptom Scale- I (PSS) | Measured 4 and 12 weeks post-trauma | No |
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