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Levetiracetam in Post-Traumatic Stress Disorder — PTSD  

Post-Traumatic Stress Disorder Clinical Trial

Official title:
A Double-Blind Discontinuation Study of Levetiracetam in Post- Traumatic Stress Disorder

Clinical Trial Summary

The purpose of this study is to evaluate the short-term efficacy and safety of levetiracetam in post-traumatic stress disorder (PTSD) and to evaluate continuation effects of levetiracetam in preventing PTSD relapse. The hypothesis is that levetiracetam will be safe and effective in preventing relapse of PTSD.

Clinical Trial Description

This is an investigator-initiated, single site study, consisting of two phases: 8 weeks of open label treatment with levetiracetam (500-2000 mg/day) in patients with PTSD, and in those who demonstrate at least minimal improvement, 12 weeks of randomized, double-blind treatment with either levetiracetam or matching placebo. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00413296
Study type Interventional
Source Duke University
Contact
Status Completed
Phase Phase 2/Phase 3
Start date November 2005
Completion date March 2008
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