Misoprostol Before and After Cesarean Section

Post Partum Hemorrhage Clinical Trial

Official title:

The Effect of Misoprostol Given Preoperative Versus Postoperative on Blood Loss With Elective Cesarean Section: Randomized Controlled Trial

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT03463070
• Other study ID #: 1122345
• Status: Not yet recruiting
• Phase: Phase 3
• First received: March 4, 2018
• Last updated: March 12, 2018
• Start date: March 2018
• Est. completion date: September 2018

Study information

• Verified date: March 2018
• Source: Kasr El Aini Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

comparison of the effect of misoprostol before and after cesarean on the blood loss

Description:

70 women who received 600 mg misoprostol rectally preoperatively versus 70 women who received 600 mg misoprostol postoperatively at operating theatre

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 140
• Est. completion date: September 2018
• Est. primary completion date: September 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• Women not in active labor have reactive non-stress test.

• No contraindications to prostaglandins.

• Have no history of coagulopathy.

Exclusion Criteria:

• Placenta previa.

• Maternal hypertension.

• Diabetes mellitus.

• Previous CS and those with active labor.

• Multiple Fibroid uterus.

• Multiple pregnancies or polyhydramnios.

• Previous myomectomy, previous history of PPH.

Related Conditions & MeSH terms

• Hemorrhage
• Post Partum Hemorrhage
• Postpartum Hemorrhage

Intervention

Drug:
• rectal misoprostol 600mg
70 women who received 600 mg misoprostol postoperatively at operating theatre

Locations

Country	Name	City	State
Egypt	Kasr El Ainiy Hospital	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
sarah mohamed hassan

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	intraoperative blood loss	Difference in weight of linen towels (gm)+Volume of contents of suction bottle (ml)	the operation time
Primary	postoperative blood loss	weighing the soaked napkins after collection of soaked towel	every 6 hours during first 24 hours.