Clinical Trials Logo
  1. Home
  2. Post Partum Hemorrhage
  3. NCT04353544
  4. Details
NCT04353544 Clinical Trial

Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery

Post Partum Hemorrhage Clinical Trial

Official title:
Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Spontaneous Vaginal Delivery

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04353544
Other study ID # 1/04-18OST
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 16, 2020
Est. completion date May 1, 2021

Study information
Verified date August 2021
Source Federico II University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Policies for timing of cord clamping vary, with early cord clamping generally carried out in the first 60 seconds aLer birth, whereas latercord clamping usually involves clamping the umbilical cord greater than one minute after the birth or when cord pulsation has ceased

Recruitment information / eligibility
Status Completed
Enrollment 122
Est. completion date May 1, 2021
Est. primary completion date February 25, 2021
Accepts healthy volunteers No
Gender Female
Age group N/A and older
Eligibility Inclusion Criteria: - singleton pregnancy - at term - cephalic presentation - spontaneous labor - spontaneous vaginal delivery Exclusion Criteria: - multiple gestation - preterm gestation - induced labor - operative delivery - hypertension or preeclampsia - fetal anomaly - abnormal placentation - planned cord blood banking - maternal bleeding disorder

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• delayed cord clamping
delayed cord clamping

Locations
Country Name City State
Italy Casa di Cura Accreditata Fabia Mater, Rome, Italy Rome Roma

Sponsors (2)
Lead Sponsor Collaborator
Federico II University Casa di Cura Accreditata Fabia Mater, Rome, Italy

Country where clinical trial is conducted

Italy, 

Outcome
Type Measure Description Time frame Safety issue
Primary change in maternal hemoglobin level on post delivery day 1 compared with the predelivery hemoglobin level The primary outcome was an objective measure of maternal blood loss: the change in maternal hemoglobin level on postdelivery day 1 compared with the predelivery hemoglobin level. day 1 after delivery
Secondary postpartum hemorrhage defined as estimated blood loss>500cc at the time of delivery
Secondary uterotonic administration at the time of delivery
Secondary need for blood transfusion at the time of delivery
Secondary jaundice neonatal jaundice day 10 of life
See also
  Status Clinical Trial Phase
Completed NCT03680339 - The Effect of Preoperative and Post Operative Misoprostol Administration on Intraoperative Blood Loss and Postpartum Hemorrhage in CS Phase 4
Completed NCT03693599 - Carbetocin Versus Syntometrine in Obese Women Undergoing Elective Cesarean Phase 4
Completed NCT03707132 - Tourniquet Reduces Blood Loss in Postpartum Hemorrhage During Hysterectomy for Placenta Accreta
Recruiting NCT02306733 - Ergometrine Versus Oxytocin in the Management of Atonic Post-partum Haemorrhage (PPH) in Women Delivered Vaginally Phase 3
Completed NCT01866241 - Combating Maternal Mortality in Uganda: An Assessment of the Role of Misoprostol in Prevention of Post-Partum Hemorrhage Phase 3
Not yet recruiting NCT01236482 - Oxytocin in Cesarean Delivery Phase 4
Completed NCT03784794 - Patient Blood Management for Massive Obstetric Hemorrhage N/A
Enrolling by invitation NCT06255496 - QStat Cartridge in Obstetric Patients
Recruiting NCT04401839 - Amr Maneuver for Prevention of Postpartum Hemorrhage N/A
Recruiting NCT06219538 - DAISY Uterine Drain Device Evaluation N/A
Not yet recruiting NCT06333340 - Comparative Efficacy of Carbetocin and Oxytocin in Parturients at Risk of Atonic Postpartum Hemorrhage Undergoing Elective Cesarean Delivery N/A
Completed NCT01863706 - Misoprostol Versus Oxytocin for Prevention of Post Partum Hemorrhage Phase 1
Not yet recruiting NCT05488457 - Oxytocin Pharmacokinetics and Pharmacodynamics Phase 2
Terminated NCT04277962 - Estimating Blood Loss Using TritonTM in Vaginal Deliveries: A Validation Trial N/A
Completed NCT04723979 - NovoSeven® in Severe Postpartum Haemorrhage - Experiences From UK, DK, FR, NL
Completed NCT03570723 - Glove-loaded Foley's Catheter Tamponade for Cesarean Section for Placenta Previa N/A
Completed NCT03117647 - Mansoura-VV Uterine Compression Suture for Primary Atonic Postpartum Hemorrhage N/A
Active, not recruiting NCT03069859 - Use of TXA to Prevent Postpartum Hemorrhage Phase 2
Not yet recruiting NCT03891082 - A Comparative Study Between Bakri Balloon and B Lynch Suture Used to Control Primary Postpartum Hemorrhage After Cesarean Section N/A
Not yet recruiting NCT03463070 - Misoprostol Before and After Cesarean Section Phase 3