Temperature Rise Caused by Short or Long-wavelengths

Status Not yet recruiting

Clinical Trial Summary

Red light has been shown to be less harmful than blue light in vitro and in vivo. Although red light has been already introduced in the market and is currently being used in patients for several reasons, no data exist on the use of red light applied to restorative procedures. This study aims to specifically measure the in vivo temperature rise in simulated restorative procedures using blue light (standard) and red light and its post-operative sensitivity rates.

Clinical Trial Description

Light-cured materials revolutionized dentistry as they allowed to control the setting of the materials in a timely manner simply upon light exposure. Although blue light has been routinely used to cure dental restorative materials for over 50 years, there are still potential risks to dental patients. These risks include gingiva burn or recession and pulp inflammation that can lead to necrosis in more severe situations due to the heat generated by this short wavelength (blue light). In addition, blue light has direct deleterious effects on cells, including irreversible imbalance in reactive oxygen species (ROS), damage to the mitochondrial DNA, and promoting collagen degradation. On the other hand, long wavelengths (such as red light) are known to have opposite effects, reducing inflammation and increasing cell proliferation. Although red light has been already introduced in the market and is currently being used in patients for several reasons, no in vivo data exist on the use of red-light applied to restorative procedures. Thus, this study aims to specifically measure the in vivo temperature rise in the tooth and gingival tissues surrounding restorative procedures using blue light (standard of care) and red light (investigational device) and evaluate/compare its post-operative sensitivity rates. The research hypothesis is that red light will generate less heat and less post-operative sensitivity than blue light (standard of care) while being used in dental restorative procedures. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06418958
Study type	Interventional
Source	University of Florida
Contact
Status	Not yet recruiting
Phase	N/A
Start date	January 13, 2025
Completion date	January 13, 2027

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02489526` - Evaluate the Analgesic Efficacy and Safety of VVZ-149 Injections for Post-Operative Pain Following Colorectal Surgery	Phase 2
Completed	`NCT05635916` - Trial of Liposomal Bupivacaine for TKA	Phase 4
Terminated	`NCT05146453` - Sternotomies and PectoIntercostal Fascia Blocks in Fast-Track Cardiac Anesthesiology	Phase 4
Recruiting	`NCT06028126` - Superficial Parasternal Intercostal Plane Block in Cardiac Surgery Trial	N/A
Not yet recruiting	`NCT03591172` - Using Three Different Final Irrigants and Showing Their Effects on the Success of Revascularization	N/A
Completed	`NCT01686802` - Post-operative Oral Morphine Versus Ibuprofen	Phase 2
Completed	`NCT01667445` - Evaluation of the Use of Spinal Epimorph in Total Knee Arthroplasty	Phase 4
Completed	`NCT01444924` - Transversus Abdominis Plane Blocks for Patients Undergoing Robotic Gynecologic Oncology Surgery	Phase 2
Completed	`NCT00830089` - Trial of a Transversus Abdominis Plane (TAP) Block in Laparoscopic Colorectal Surgery	N/A
Completed	`NCT00968955` - Effect of Local Infiltration Analgesia in Total Hip Arthroplasty	Phase 4
Terminated	`NCT00875862` - Shoulder Adhesive Capsulitis and Ambulatory Continuous Interscalene Nerve Blocks	Phase 4
Completed	`NCT00847093` - LMX-4 for Postoperative Pain Management in Infants and Children Undergoing Penoplasty Surgery	Phase 4
Completed	`NCT00390312` - Efficacy and Safety of Intranasal Morphine for Pain After Third Molar Extraction	Phase 2
Recruiting	`NCT05278494` - Dextromethorphan for Treatment of Postoperative Pain	N/A
Recruiting	`NCT05973045` - Investigation of the Effect of Distention Medium Temperature on Image Quality, Hyponatremia Risk, and Post-operative Pain in Operative Hysteroscopy	N/A
Not yet recruiting	`NCT04999670` - Fascial Closure and Post-caesarean Pain	N/A
Enrolling by invitation	`NCT04346407` - Dronabinol for Post-operative Pain After Lumbar Fusion	Phase 4
Completed	`NCT03635515` - Occurrence of Post-op Pain Following Gentlewave	N/A
Terminated	`NCT03201809` - Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial	N/A
Completed	`NCT03254056` - Fascial Closure Techniques Post-Operative Pain Laparoscopy	N/A