Analgesic Efficacy of Genicular Nerve Block Versus (IPack Block ) in Patients Undergoing (ACL) Repair

Post Operative Pain Clinical Trial

Official title:

Analgesic Efficacy of Genicular Nerve Block Versus Local Anaesthetic Infiltration Between Popliteal Artery and Capsule of the Knee (IPACK Block ) in Patients Undergoing Anterior Cruciate Ligament (ACL) Repair by Knee Arthroscopy . A Randomized Controlled Prospective Study .

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06404658
• Other study ID #: FMBSUREC/02012024/Kamal
• Status: Recruiting
• Phase: N/A
• Start date: May 12, 2024
• Est. completion date: October 30, 2024

Study information

• Verified date: May 2024
• Source: Beni-Suef University
• Contact: Mariana AbdElsayed Mansour
• Phone: 01222960009
• Email: mrmrsyk4[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

One of the most common injuries to the knee is an anterior cruciate ligament (ACL) sprain or tear due to trauma ACL damage is crippling and often requires repair with an arthroscopic method, which is an outpatient surgery. Nevertheless, patients experience severe postoperative pain on the first day after the ACL reconstruction.Efficient postsurgery pain management is an important part of patient recovery that is also crucial for their satisfaction.

Description:

The optimum role of peripheral nerve blocks in ACL reconstruction continue to be debated as a component of multi-modal analgesia . As such ,an ideal block for ACLR would target sensation but not motor function,have minimal complication risk,and be easily reproducible The genicular nerves include branches from the femoral, common peroneal, saphenous, tibial, and obturator nerves which innervate the knee capsule . The superolateral, superomedial, and inferomedial On the other hand, the interspace between the Popliteal Artery and Capsule of the Knee (IPACK) block provides analgesia on the posterior knee joint, and the application of a genicular or IPACK block has been be associated with promising outcomes following the ACLR surgery

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: October 30, 2024
• Est. primary completion date: October 30, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 15 Years to 45 Years

Eligibility

Inclusion Criteria:

• Patient age from 18 to 45 years old Patient status ASA I - II Patient body mass index (BMI) <40 kg/m2

Exclusion Criteria:

• -Patients were excluded if they refused consent.

• Patients who are Not cooperative.

• BMI >40 kg/m2.

• Allergy to local anesthetics.

• Patients with anticoagulation or bleeding problems.

• Previous nerve dysfunction.

• Physical status ASA class IV.

Related Conditions & MeSH terms

• Pain, Postoperative
• Post Operative Pain

Intervention

Procedure:
• Genicular nerve block
patients who receive Genicular nerve block with spinal anathesia .

Locations

Country	Name	City	State
Egypt	Benisuef University Hospital	Benisuef

Sponsors (1)

Lead Sponsor	Collaborator
Beni-Suef University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	VAS score	Measuring pain intensity regarding mean visual analogue score (VAS score ) ranging from 0 (no pain) to 10 (the worst imaginable pain.	48 hour
Secondary	Ambulatory score	Ambulatory score from ( 0 to 2) (score of 0) is assigned if the activity cannot be performed despite substantial help; (score of 1 )is assigned if the activity is performed using personal physical support.; (score of 2) is assigned if the activity is performed independently.	Within 48 hour
Secondary	Time of first rescue analgesia	the time to ask for the first post operative analgesia	within 24 hour
Secondary	Total opioid consumption post operative	Total opioid consumption post operative	Within 24 hour
Secondary	Incidence of occurrence of systemic toxicity	( hypotension ,arrthymias, bradycardia, cardiac arrest, oral numbness and convulsions	Within 24 hour
Secondary	The length of hospital stay .	The length of hospital stay .	within one week