Proximal Versus Distal Adductor Canal Blocks for Total Knee Arthroplasty

Post-Operative Pain Clinical Trial

Official title:

A Comparison of Proximal Versus Distal Continuous Adductor Canal Blocks After Total Knee Arthroplasty

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02701114
• Other study ID #: IRB15118
• Status: Completed
• Phase: N/A
• First received: February 29, 2016
• Last updated: July 11, 2017
• Start date: February 2016
• Est. completion date: November 2016

Study information

• Verified date: July 2017
• Source: Benaroya Research Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study is designed to evaluate pain control of continuous adductor canal blocks placed proximally versus distally within the canal. The investigators hypothesize that there will be similar pain control between both groups.

Description:

This study is a non-inferiority trial designed to determine whether placement of a continuous block within the adductor canal has a substantial impact on pain following total knee arthroplasty. Our primary outcome to determine this difference will be opioid consumption within the first day following surgery. Secondary outcomes will include: pain scores, quadriceps strength, and distance ambulated during physical therapy.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 76
• Est. completion date: November 2016
• Est. primary completion date: November 2016
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Unilateral Total Knee Arthroplasty

• ASA physical status I-III

• >18 years old

• Non-pregnant

• Consent to participate in the study

Exclusion Criteria:

• Refusal to participate

• <18 years old

• Chronic opioid use

• Localized infection Pregnancy Pre-existing coagulopathy Allergy to ultrasound gel or local anesthetics Contraindication to or refusal of spinal anesthetic

Related Conditions & MeSH terms

• Pain, Postoperative
• Post-Operative Pain

Intervention

Procedure:
• Proximal Adductor Canal Block
Continuous Nerve Block
• Distal Adductor Canal Block
Continuous Nerve Block

Locations

Country	Name	City	State
United States	Virginia Mason Medical Center	Seattle	Washington

Sponsors (1)

Lead Sponsor	Collaborator
Benaroya Research Institute

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Opioid Consumption (IV Morphine Equivalents)	Total opioid consumption	24 Hours
Secondary	Opioid Consumption (IV Morphine Equivalents)	Total opioid consumption	48 Hours
Secondary	Pain (Numeric Rating)	NRS Pain Scale	48 Hours
Secondary	Quadriceps Strength (% of Baseline)	Maximum Isometric Voluntary Contraction	48 Hours
Secondary	Distance Ambulated (Feet)	Total distance ambulated during physical therapy	48 Hours