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Post-Op Complication clinical trials

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NCT ID: NCT04400721 Not yet recruiting - Pain, Postoperative Clinical Trials

Efficacy of an Erector Spinae Plane Block in VATS/RATS

ESPAM
Start date: July 1, 2020
Phase: Phase 3
Study type: Interventional

This study aims to study the analgesic and respiratory effects of the erector spinae plane block for patients undergoing video-assisted thoracic surgery (VATS) or robotic assisted thoracic surgery (RATS).

NCT ID: NCT04364477 Completed - Pain, Postoperative Clinical Trials

TAP Block On Abdominal Surgery Patients With General Anesthesia

TAPBLOCK
Start date: January 4, 2015
Phase: N/A
Study type: Interventional

INTRODUCTION: The aim of this study was to investigate the effects of tranversus abdominis plane (TAP) block placed postoperatively using ultrasound guidance for patients with caesarean section, myomectomy and hysterectomy under general anesthesia by eliminating additional pain caused by surgical incision. MATERIALS AND METHODS: The study has been planned to investigate the postoperative analgesia of 50 patients with TAP blocks applied and non-applied between the ages of 18-65, who will pass abdominal surgery. Study has been conducted in a prospective, randomized and controlled manner. Patients have been classified as those who have undergone TAP block (group: I) and those without block (group: II).

NCT ID: NCT04301232 Completed - Clinical trials for Post-Op Complication

Fast-Track Eligibility and Hospital Discharge for Outpatient Lumbar Discectomy

Start date: May 10, 2018
Phase:
Study type: Observational [Patient Registry]

122 ASA I-II patients were enrolled into the study. IV propofol, fentanyl and rocuronium were used for the induction and a total intravenous anesthesia technique for the maintenance of anesthesia. Sugammadex was given for neuromuscular blockade reversal. A multi-modal analgesic regimen was utilized. Primary outcome measures were PACU bypass rates and hospital discharge times. Secondary outcome measure was to compare discharge scoring systems for PACU bypass assessment: modified Aldrete Scoring System (mASS), White's Fast-Tracking Scoring System (WFTSS), and SPEEDS criteria

NCT ID: NCT04293653 Active, not recruiting - Frailty Clinical Trials

Protocol for Patients Above 75 Years Undergoing Emergency Laparotomy

(ProPEL)
Start date: January 21, 2020
Phase: N/A
Study type: Interventional

In the ProPEL study the effect of a protocol designed for elderly patients about to undergo emergency abdominal surgery will be investigated. The protocol addresses issues of both frailty and ceiling-of -care decisions.

NCT ID: NCT04268576 Completed - Clinical trials for Post-Op Complication

Impact of an Improved Rehabilitation Program After a Scheduled Hysterectomy.

RAACHYS
Start date: November 18, 2019
Phase:
Study type: Observational

It is an observational study, prospective in order to assess the impact of the implementation of an early rehabilitation program on post-operative recovery. this is measured by the qOR15 questionnaire in patients operated on for a programmed hysterectomy, it takes place in the gynecology department of the CHR Metz-Thionville hospital.

NCT ID: NCT04197869 Completed - Constipation Clinical Trials

Does a Preoperative Bowel Regimen Change Time to First Bowel Movement After Robotic Sacral Colpopexy

Start date: December 9, 2019
Phase: Phase 4
Study type: Interventional

The hypothesis is that starting a bowel regimen with Polyethylene Glycol prior to robotic assisted sacrocolpopexy will decrease time to first bowel movement after surgery. The experimental group will take a pre-operative course of polyethylene glycol daily for seven days prior to procedure date. The control group will not be given any intervention preoperatively. All patients will take polyethylene glycol postoperatively.

NCT ID: NCT04194060 Completed - Emergencies Clinical Trials

ERAS vs Conventional Approach in Peptic Perforation-RCT

ERASE
Start date: January 20, 2020
Phase: N/A
Study type: Interventional

This study compares 2 different ways of perioperative management in patients of peptic perforation. Experimental arm is the ERAS arm( Enhanced recovery after surgery) and the comparative arm is Conventional arm.

NCT ID: NCT04188093 Completed - Clinical trials for Post-Op Complication

Identifying Patients in Risk of Post-operative Complications Using PACU Discharge Criteria

Start date: January 1, 2018
Phase:
Study type: Observational

In the Postoperative Care Unit surgical patients are monitored closely to ensure safe condition before transfer to the ward. This study will aim to identify patients in risk of complications on the ward using the national postanesthesia care unit (PACU) discharge criteria, a modified Aldretes score. Secondary to identify patients in risk of micro events as detected by continuous monitoring of vital signs on the ward.

NCT ID: NCT04168307 Completed - Clinical trials for Post-Op Complication

Physiotherapy Versus Use of a New Ankle Trainer Device After Ankle Fracture Operation.

Start date: November 29, 2014
Phase: N/A
Study type: Interventional

The study will compare the functions outcomes between two different rehabilitation protocol after operated weber b ankle fractures

NCT ID: NCT04117568 Terminated - Sepsis Clinical Trials

The Role of Emergency Neutrophils and Glycans in Postoperative and Septic Patients

Start date: September 4, 2019
Phase:
Study type: Observational

Surgical trauma elicits an immune response aiming to initiate healing and remove debris and damaged tissue locally at the wound site (1). This local reaction includes a considerable production of cytokines and chemokines that enters the circulation and initiate a systemic inflammatory response mediated by circulating cytokines and chemokines. This response is called systemic inflammatory immune response (SIRS) and is an aseptic systemic inflammation. Postoperative inflammation produces proinflammatory cytokines, mainly IL-6, IL1 beta, and tumor necrosis factor alfa (2). Neutrophils and emergency granulopoesis Polymorphonuclear neutrophils constitute the most abundant population of white blood cells. Their main task is to provide innate immune protection of the host from microbial attack, migrating to the site of infection, engulfing the microbes by phagocytosis, and killing the prey through attack by reactive oxygen species (ROS) and antimicrobial granule pro¬teins (22). Upon systemic infection or inflammation, e.g., sepsis or trauma, the bone marrow enters a state of emergency granulopoiesis, drenched in cytokines that augment production and survival of neutrophils for rapid delivery to the blood (23-25). Recently, advanced techniques have evolved that al¬low the isolation of different developmental stages of steady-state and emergency neutrophils, and characterization of these has just begun (26). Glycans Glycans (polysaccharides) attached to proteins and lipids on the surfaces on immune cells serve as ligands for glycan-binding proteins, lectins. Several neutrophil processes are directed by gly¬can - lectin interactions; selectin-directed rolling on the endothelium, siglec-mediated in¬hibitory signals, and activation of effector function by galectins. Many of the proteins that end up in neutrophil intra-cellular granules are highly glycosylated, but not much is known about if and how the neutrophil glycome evolves during the 'targeting-by-timing' process of differentiation and how this is affected by emergency granulopoiesis during systemic infection and inflammation. Here is a clear knowledge gap.