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Post-Dural Puncture Headache clinical trials

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NCT ID: NCT02150304 Completed - Clinical trials for Postdural Puncture Headache

Aminophylline Prophylaxis For Postdural Puncture Headache

Start date: January 2014
Phase: N/A
Study type: Observational

postdural puncture headache is a rare but serious complication of spinal anesthesia. many drugs were studied in prevention or treatment of that complication. However, there are limited numbers of trials about intravenous aminophylline for prevention. because of that we retrospectively aimed to investigate the effectiveness of aminophylline for postdural puncture headache in cesarean section.

NCT ID: NCT02149680 Completed - Clinical trials for Post-dural Puncture Headache

Long-term Effects of Accidental Dural Puncture in Patients Having Had an Epidural Blood Patch (LEAP)

LEAP
Start date: January 2014
Phase: N/A
Study type: Observational

Accidental dural puncture (ADP) during placement of an epidural catheter for anesthesia and analgesia is a well known complication. Previous studies have found audiometric deterioration following ADP. Epidural blood patch (EBP) is a common method for treating postural headache in patients with accidental dural puncture. In most cases, one-two patches are needed for successful management. Long-term effects of EBP on the incidence of backache, headache and early audiometric deterioration are few or non-existant. The present study aims to determine the long-term sequelae of EDP in parturients who had ADP and were treated with an EBP during the years 2005 - 2011.

NCT ID: NCT02122419 Completed - Pregnancy Clinical Trials

The Effect of Patient Position on Postdural Puncture Headache

Start date: April 2014
Phase: N/A
Study type: Observational

We aimed to investigate the association between the position in which spinal anesthesia was performed and postdural puncture headache occurrence.

NCT ID: NCT01977898 Completed - Clinical trials for Postdural Puncture Headache

Incidence of Headache Following an Unintentional Dural Puncture

Start date: November 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the use of intrathecal morphine administration following an unintentional dural puncture, to decrease the incidence of post dural puncture headaches (PDPH) in obstetric patients.

NCT ID: NCT01821807 Completed - Clinical trials for Complications; Anesthesia, Spinal and Epidural, in Pregnancy

Comparison of Two Spinal Needles Regarding Postdural Puncture Headache

Start date: June 2013
Phase: N/A
Study type: Observational

The aim of the study is to observe the rate of postdural puncture headache observed after spinal anesthesia in cesarean section patients. Two kind of spinal anesthesia needles will be used: 1. 26 Gauge Quincke (cutting-tip needle) 2. 26 Gauge Atraucan (atraumatic needle) The investigators will observe: 1. Number of spinal punctures 2. Time required for the spinal anesthesia procedure Patients will be evaluated after 7 days for: 1. Headache 2. Backache

NCT ID: NCT01503788 Not yet recruiting - Clinical trials for Post Dural Puncture Headache

Bedside Sedation for the Prevention of Post Dural Puncture Headache

Start date: February 2012
Phase: Phase 2
Study type: Interventional

Dural or lumbar puncture (LP), the passing of a needle into the space of the spinal cord, is a common procedure in everyday clinical practice. The most common use for LP is to measure the spinal fluid pressure and sample spinal fluid for laboratory analysis. However, it is also used for therapeutic purposes, such as administering chemotherapy or spinal anesthesia. A notorious side effect of dural puncture is headache that ranges from mild to debilitating and may last for several days following the procedure. Among diagnosed patients, 39% experience at least 1 week of impaired ability to perform activities of daily living. The likelihood of developing a headache after dural puncture depends on a number of factors. As fluid leak is assumed to be the culprit mechanism in this headache strategies to minimize the leak seem to offer the best path to lowering the incidence of headache after diagnostic LP, the commonest clinical context of dural puncture in medical practice. Lumbar puncture is a highly stressful event for most patients. As both pain and anxiety cause adrenergic stimulation, they also cause an increase in ICP. We believe that this mild increase in ICP, occurring before the puncture as well as during the puncture itself may exacerbate the pressure difference between the CSF space and the epidural space and so worsen the CSF leak Furthermore, this excess pressure, although mild, might cause the dural puncture hole to widen slightly and so further augment the leak and possibly even prolong it. Furthermore, the very anticipation of pain causes a rise in neurotransmitters that may cause a sensitization effect and worsen pain. This increase in adrenergic drive as well as the sensitization to pain can be effectively blunted by the periprocedural use of mild IV sedation. Benzodiazepines, with their sedative-hypnotic qualities are well suited for this task. This study aims to test the effect of mild peri-procedural IV sedation using Midazolam on the rates of headache after diagnostic LP. Patients undergoing a diagnostic LP will be randomized into two groups. Group 1 will undergo the procedure as routinely practiced. Group 2 will be given Midazolam IV 10-5 minutes prior to the procedure and undergo the same diagnostic procedure. All patients in the study will remain under observation in the hospital for at least 6 hours. Patients will be evaluated for headache and specifically for headache. Clinical follow up will continue for 72 hours by administering a short questionnaire over the telephone.

NCT ID: NCT01481922 Recruiting - Clinical trials for Post-lumbar Puncture Headache

What Needle Diameter Should Physician Use When They Perform Lumbar Puncture ? A Randomized Controlled Trial

Start date: November 2011
Phase: Phase 4
Study type: Interventional

This study is intended to help guide the choice of needle diameter when performing a lumbar puncture. Smaller spinal needles have been shown to decrease rate of adverse events such as post-lumbar puncture headache and hearing loss. The main drawback to using smaller needles is diminished flow rate; some textbooks recommend using needles no smaller than 22 gauge because of the slow flow rate though others recommend smaller needles, namely 22-24 gauge. Some authors have described a successful use of spinal needles as small as 25 gauge when performing a lumbar puncture. The investigators do not believe that the flow-rate difference between 22 and 24 gauge needles is significant enough to justify using the larger needles. The investigators trial will compare the Whitacre 22 gauge and Whitacre 24 gauge needles for flow rate, and incidence of the known complications of pain during procedure and backache at 8 and 15 days post-procedure. The investigators will also look at whether smaller needles are associated with less pain during the procedure and less backache the next 2 weeks after the procedure.

NCT ID: NCT01448590 Withdrawn - Clinical trials for Post Dural Puncture Headache

Post Dural Puncture Headache After Accidental Dural Puncture

Start date: June 2011
Phase: N/A
Study type: Observational

Epidural anesthesia is associated with potential risks and complications, post dural puncture headache (PDPH) one of the most recognized with epidural or spinal anesthesia. Accidental dural punctures occur with approximately 1.5% of all epidural attempts. Studies have suggested that the use of an intrathecal catheter reduces the incidence of PDPH. A systematic review of the existing literature will identify if there is reliable evidence to support this theory. A secondary outcome, headache severity, will also be explored via incidence rates of epidural blood patch, as this intervention is performed as a treatment for the most severe headaches.

NCT ID: NCT00809627 Completed - Clinical trials for Post Dural Puncture Headache

Caffeine Versus Placebo for Spinal Headaches

Start date: January 2007
Phase: N/A
Study type: Interventional

Caffeine will be studied against placebo in patients with positional headache after a lumbar puncture (aka "spinal headache").

NCT ID: NCT00465166 Completed - Clinical trials for Postdural Puncture Headache

Lumbar Spine Ultrasound of Patients With Previous Accidental Dural Puncture During Labour Epidural

Start date: February 2007
Phase: N/A
Study type: Observational

Accidental dural puncture is a potential complication of epidural analgesia for labour and delivery. When it happens, it may cause debilitating headaches and other symptoms that prevent mothers from talking care of their newborns. Accidental dural puncture is related to the operator performance and to individual anatomical variations of the spine. The purpose of this study is to do a lumbar spine ultrasound on the patients who have had accidental dural punctures and analyze if there is any abnormal anatomy seen. Then, we will compare the position of any spinal abnormality to the position of the dural puncture reported in the anaesthesia record.