High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome

Polycystic Ovary Syndrome Clinical Trial

Official title:

High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome. A Randomized Controlled Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01919281
• Other study ID #: 2013/886
• Status: Completed
• Phase: N/A
• First received: July 17, 2013
• Last updated: September 28, 2015
• Start date: July 2013
• Est. completion date: April 2015

Study information

• Verified date: May 2015
• Source: Norwegian University of Science and Technology
• Contact: n/a
• Is FDA regulated: No
• Health authority: Norway:National Committee for Medical and Health Research Ethics
• Study type: Interventional

Clinical Trial Summary

The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic Ovary Syndrome (PCOS).

Few studies have examined the effect of strength training alone on insulin sensitivity, reproductive outcomes and body composition in women with PCOS. Most previous studies on aerobic exercise in PCOS have applied moderate exercise intensity.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: April 2015
• Est. primary completion date: January 2014
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Women

• Age 18-45 years old

• PCOS

Exclusion Criteria:

• Regular high intensity endurance or strength training (two or more times per week of vigorous exercise).

• Concurrent treatments (insulin sensitizers or drugs known to affect gonadotropin or ovulation, with a wash out period of 1 months prior to inclusion).

• On-going pregnancy.

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Polycystic Ovary Syndrome
• Syndrome

Intervention

Behavioral:
• strength training

• interval training

Locations

Country	Name	City	State
Norway	Department of circulation and medical imaging , NTNU	Trondheim

Sponsors (1)

Lead Sponsor	Collaborator
Norwegian University of Science and Technology

Country where clinical trial is conducted

Norway, 

References & Publications (1)

Almenning I, Rieber-Mohn A, Lundgren KM, Shetelig Løvvik T, Garnæs KK, Moholdt T. Effects of High Intensity Interval Training and Strength Training on Metabolic, Cardiovascular and Hormonal Outcomes in Women with Polycystic Ovary Syndrome: A Pilot Study. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Menstruation diary		up to 6 months	No
Primary	insulin resistance	measured with the homeostatic model assessment for insulin resistance (HOMA-IR) method	10 weeks	No
Secondary	Body composition	Measured as body fat % on an impedance scale and waist circumference	10 weeks	No
Secondary	Maximum oxygen uptake	Measured during maximum effort exercise test	10 weeks	No
Secondary	Endothelial function	Flow mediated dilatation of the brachial artery.	10 weeks	No