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Targeting of Immune Response After Pneumococcal Vaccination — PncHR  

Pneumococcal Pneumonia Clinical Trial

Official title:
Comparison of Immune Response in Pneumococcal Pneumonia and After Vaccination

Clinical Trial Summary

Pneumococcal polysaccharide vaccine does not confer protection against noninvasive pneumonia. The study aims to compare lymphocyte homing in pneumonia and in those receiving Pnc polysaccharide vaccine (PPV) or Pnc conjugate vaccine (PCV)

Clinical Trial Description

Pneumococcal polysaccharide vaccine does not confer protection against noninvasive pneumonia. The study compares the homing profiles of Pnc-specific plasmablasts in 15 patients with pneumonia and in 15 volunteers receiving Pnc polysaccharide vaccine (PPV) and 12 volunteers receiving Pnc conjugate vaccine (PCV) ;

Study Design

Allocation: Non-Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01402245
Study type Interventional
Source Helsinki University Central Hospital
Contact
Status Completed
Phase Phase 4
Start date January 2005
Completion date June 2010
View Details
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