Effect of Oral Enteral Nutrition in Pierre Robin Syndrome

Pierre Robin Syndrome Clinical Trial

Official title: Effect of Oral Versus Nasal Enteral Nutrition in Pierre Robin Syndrome: A Randomized Controlled Study

Status Completed

Clinical Trial Summary

This was a randomized controlled study. The infants enrolled were randomly divided into the IOE group (with Intermittent Oro-Esophageal Tube Feeding, n=25) and the PNG group (with Nasogastric Tube Feeding, n=23), all receiving systemic therapy. Before and after 4-week treatment, pulmonary infection, swallowing function, nutritional status and body weight between the two group were compared.

Clinical Trial Description

Pierre Robin Syndrome (PRS) can cause dysphagia. In China, persistent nasogastric tube feeding (PNG) is the mainstream choice as nutrition support in the dysphagic infants with PRS. However, PNG is associated with various complications, necessitating the exploration for a safer and more effective nutritional support approach. Therefore, this study aims to observe the clinical effect of intermittent oro-esophageal tube feeding (IOE) compared to PNG in the dysphagic infants with PRS who received systemic therapy. This was a randomized controlled study. The infants enrolled were randomly divided into the IOE group (with IOE, n=25) and the PNG group (with PNG, n=23), all receiving systemic therapy. Before and after 4-week treatment, pulmonary infection, swallowing function, nutritional status and body weight between the two group were compared. ;

Related Conditions & MeSH terms

• Pierre Robin Syndrome
• Syndrome

• NCT number: NCT06303973
• Study type: Interventional
• Source: Ahmadu Bello University Teaching Hospital
• Status: Completed
• Phase: N/A
• Start date: January 10, 2022
• Completion date: June 15, 2023