Autologous Bone Marrow Cell Treatment in Peripheral Atherosclerosis

Status Recruiting

Clinical Trial Summary

Implantation of bone marrow cells, including endothelial progenitor cells, into ischemic limbs has been shown to improve collateral vessel formation. In the present study the safety and feasibility of autologous blood mononuclear cells implantation will be investigated in patients with severe peripheral atherosclerosis.Twenty cases will be enrolled. Improvement in the ankle-brachial pressure index (ABI:>0.1), ischemic ulcers and angiography as well as laser doppler flow will be evaluated until six months.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00306085
Study type	Interventional
Source	University of Naples
Contact	Heidi Eisele
Phone	+39 081/5665685
Email	heidi.eisele@unina2.it
Status	Recruiting
Phase	Phase 1
Start date	April 2005
Completion date	April 2006

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