Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery

Periodontitis Clinical Trial

Official title:

Clinical Performance of Two 0.2% Chlorhexidine Mouth Rinses After Periodontal Surgery. A Blinded, Intra-individual Cross-over Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04223076
• Other study ID #: 2020/121314
• Status: Recruiting
• Phase: Phase 4
• Start date: March 20, 2019
• Est. completion date: December 30, 2020

Study information

• Verified date: January 2020
• Source: University of Oslo
• Contact: Erik Mauland, DDS
• Phone: 004747636914
• Email: erik.mauland[@]hotmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions. Several 0.2% solutions are available on the market. This study aimed to compare effectiveness of two commercially available 0.2% chlorhexidine mouthwashes. Patients, that after initial periodontal therapy, had a need for two periodontal surgeries, will be invited to join. After one surgical session, the patient will receive one 0.2% chlorhexidine solution, and after the next surgical session the patient will receive the other 0.2% chlorhexidine solution. Plaque and gingivitis will be recorded, as well as side effects.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 31
• Est. completion date: December 30, 2020
• Est. primary completion date: December 20, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

Periodontitis, stage III and IV

Exclusion Criteria:

Uncontrolled diabetes Systemic conditions associated with excessive bleeding Uncontrolled hypertension

Related Conditions & MeSH terms

• Dental Plaque
• Periodontal Diseases
• Periodontitis

Intervention

Drug:
• Chlorhexidine 0.2%, Corsodyl
Comparison of Corsodyl and Curasept
• Chlorhexidine 0.2%, Curasept
Chlorhexidine 0.2% mouthwash with an Anti Discoloring System (ADS)

Locations

Country	Name	City	State
Norway	Erik Mauland	Oslo

Sponsors (1)

Lead Sponsor	Collaborator
University of Oslo

Country where clinical trial is conducted

Norway, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Plaque index	Dental Plaque	14 days intervention period
Primary	Gingival Index	Gingivitis	14 days intervention period