Periodontitis Clinical Trial
Official title:
Clinical and Radiographic Evaluation of Papilla Preservation Flap With or Without Nanocrystalline Hydroxyapatite Bone Graft for Management of Periodontal Intrabony Defects: A Randomized Controlled Clinical Trial
This study is meant to assess clinically and radiographically the possible predictable results regarding the use of nanocrystalline hydroxyapatite bone graft substitute together with papilla preservation flap versus papilla preservation flap alone in the treatment of periodontal intrabony defects. Patients will be randomly assigned to either test or control group. The two groups will be equally prepared for both surgical procedures. Then the decision of which group will receive (PPF techniques + Nanocrystalline hydroxyapatite bone graft) and which will receive (PPF techniques only) will be taken.
Status | Not yet recruiting |
Enrollment | 12 |
Est. completion date | November 1, 2019 |
Est. primary completion date | September 1, 2019 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 25 Years to 50 Years |
Eligibility |
Inclusion Criteria: - Patient-related criteria: - Patient consulting in the outpatient clinic. - Able to tolerate surgical periodontal procedures. - Patient ready to perform oral hygiene instructions. - Compliance with the maintenance program. - Provide informed consent. - Accepts the 6 months follow-up period. Teeth related criteria: - Mature permanent tooth. - Tooth with two or three-walled intra-bony defect, CAL = 5mm with intra osseous defect = 3mm. Exclusion Criteria: - Patient-related criteria: - Medically compromised patients. - Pregnant or nursing women. - Uncooperative patients. - Smokers. Teeth related criteria: - Teeth with one wall intra-bony defect. - Teeth with supra-bony defects. - Teeth with grade II or III mobility. - Teeth with proximal carious defects or proximal faulty restorations. |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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Cairo University |
Heinz B, Kasaj A, Teich M, Jepsen S. Clinical effects of nanocrystalline hydroxyapatite paste in the treatment of intrabony periodontal defects: a randomized controlled clinical study. Clin Oral Investig. 2010 Oct;14(5):525-31. doi: 10.1007/s00784-009-032 — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical attachment level | Measured from the CEJ to the bottom of the gingival sulcus by William's graduated Periodontal probe in mm | 6 months | |
Secondary | Probing Depth | Measured from the gingival margin to the bottom of the gingival sulcus by William's graduated Periodontal probe in mm | 6 months | |
Secondary | Gingival Recession Depth | Measured from the CEJ to the most apical extension of the gingival margin by William's graduated Periodontal probe in mm | 6 months | |
Secondary | Plaque index | Numerical Scoring system Scores 0,1,2,3 by William's graduated Periodontal probe | 6 months | |
Secondary | Gingival index | Numerical Scoring system Scores 0,1,2,3 by William's graduated Periodontal probe | 6 months | |
Secondary | Linear bone fill | Measured from the CEJ to the deepest part of the intrabony defect using the linear measurement tool of the Digora software | 6 months |
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