Periodontal Disease Prevention Study

Status Completed

Clinical Trial Summary

This study is one component of a program to improve the maintenance of good dental health and the prevention of disease by use of risk stratification methods to efficiently guide increased preventive services to adult dental patients who are at increased risk for the major dental diseases, caries and adult periodontitis.

The investigators will use a retrospective cohort model to analyze a large dental claims database to determine if the frequency of preventive services influenced the periodontal disease outcomes and to determine if periodontal risk assessment information can be used to stratify dental patients into "high risk" and "low risk" categories that influence the effect of preventive services on periodontitis outcomes.

Primary Objective To evaluate whether dental patients who are classified as "low risk" for periodontal disease progression, based on history of periodontitis (claims history), smoking, diabetes, and IL-1 genetic variations, have different primary and secondary endpoints if they had two dental cleanings per year compared to one cleaning per year.

Secondary Objectives To evaluate whether dental patients who are classified as "high risk" for periodontal disease progression, based on a history of periodontitis, smoking, diabetes, and IL-1 genetic variations, have different primary and secondary endpoints if they had two dental cleanings per year compared to one cleaning per year.

To evaluate whether dental patients who have had one dental cleaning per year have different primary and secondary endpoints if they are classified as "low risk" for periodontal disease compared to patients who are classified as "high risk." To evaluate whether dental patients who have had two dental cleaning per year have different primary and secondary endpoints if they are classified as "low risk" for periodontal disease compared to patients who are classified as "high risk."

Clinical Trial Description

n/a

Study Design

Observational Model: Cohort, Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01584479
Study type	Observational
Source	University of Michigan
Contact
Status	Completed
Phase	N/A
Start date	December 2010
Completion date	March 2012

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04712630` - Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft	N/A
Completed	`NCT06127069` - Treatment of Residual Pockets in Periodontal Patients Using an Oscillating Chitosan Device	N/A
Completed	`NCT04964167` - Indocyanine-green Mediated Photosensitizer VS Aloe Vera Gel: Adjunct Therapy to Scaling and Root Planing in Patients With Chronic Periodontitis	Phase 4
Completed	`NCT05906797` - Impact of Non-surgical Periodontal Therapy in the Improvement of Early Endothelial Dysfunction in Subjects With Periodontitis.	N/A
Recruiting	`NCT03997552` - NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration	N/A
Completed	`NCT05530252` - Effects of AMP Application After Non-surgical Periodontal Therapy on Treatment of Periodontitis	Phase 4
Completed	`NCT04881357` - Antiplaque/Antigingivitis Effect of Lacer Oros Integral	N/A
Recruiting	`NCT03790605` - A Clinical Trial to Study the Effect of a Drug, Curcumin in Patients With Periodontitis	Phase 3
Enrolling by invitation	`NCT04971174` - Outcomes of Periodontal Regenerative Treatment
Not yet recruiting	`NCT05568290` - Interleukin-38 Levels in Individuals With Periodontitis
Completed	`NCT04383561` - Relationship Between LRG and Periodontal Disease	N/A
Recruiting	`NCT03997578` - Non-incised Papillae Surgical Approach (NIPSA) and Connective Tissue Graft Plus Emdogain for Periodontal Defects	N/A
Completed	`NCT03901066` - Smoking Dependence and Periodontitis
Enrolling by invitation	`NCT04956211` - Periodontal Treatment and Ischemic Stroke	N/A
Recruiting	`NCT05971706` - Ozone Application in Periodontal Treatment	N/A
Recruiting	`NCT06099574` - A Study on the Oral Health Status of Pregnant Women With Gestational Diabetes and Its Correlation With Oral Flora
Completed	`NCT04402996` - Meteorin-like Levels in Individuals With Periodontitis
Active, not recruiting	`NCT05311657` - Oral Health and Severe COPD
Not yet recruiting	`NCT06453278` - (DDS) in India: a Screening Tool to Identify Prediabetes and Undiagnosed Type 2 Diabetes in Dental Settings
Not yet recruiting	`NCT05643287` - The Effect of Time on the Outcome of Periodontal Treatment.	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.