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NCT06382935 Clinical Trial

Impact of Non-surgical Periodontal Treatment of miRNome

Periodontitis Clinical Trial

Official title:
Effects of Minimally Non-surgical Periodontal Treatment Versus Quadrantwise Subgingival Instrumentations on miRNome in Gingival Tissues

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06382935
Other study ID # 34-24
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date April 20, 2024
Est. completion date October 15, 2024

Study information
Verified date April 2024
Source University of Catania
Contact Gaetano Isola
Phone 0953785652
Email gaetano.isola@unict.it
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment by means of minimally invasive approach MINST or Q-SI (quadrantwise) approach in subjects with periodontitis on miRNome in gingival crevicular fluid

Description:

A double-blind randomized-controlled clinical trial is conducted in order to evaluate the impact of non-surgical periodontal treatment in subjects with periodontitis. 60 patients: 30 with periodontitis and 30 healthy controls. All the patients are assessed for clinical, periodontal, blood following of minimally invasive approach MINST or Q-SI (quadrantwise). Measurements are taken before and after initial periodontal treatment in the periodontal subjects.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date October 15, 2024
Est. primary completion date September 22, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: - Diagnosis of Periodontitis Exclusion Criteria: - Periodontal treatment - Use of antibiotics, NSAIDs, and immunosuppressants during the last 6 months - Pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Probin Pocket Depth reduction
Probin Pocket Depth reduction in millimetres before and after treatment

Locations
Country Name City State
Italy AOU Policlinico G. Rodolico Catania

Sponsors (1)
Lead Sponsor Collaborator
University of Catania

Country where clinical trial is conducted

Italy, 

Outcome
Type Measure Description Time frame Safety issue
Primary Probing Pocket Depth Reduction in Probing Pocket Depth after treatnebt 6-months
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