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CoQ10 and Omega-3 as Adjuncts to Periodontal Therapy, TAC of Saliva.

Periodontal Diseases Clinical Trial

Official title:
Comparative Evaluation of CoQ10 and Omega-3 as Adjuncts to Periodontal Therapy and Total Antioxidant Capacity of Saliva.

Clinical Trial Summary

Comparative evaluation of CoQ10 and Omega-3 as adjuncts to periodontal therapy and total antioxidant capacity of saliva (randomized Double-Blind Clinicalials)

Clinical Trial Description

This study was designed as a blind, randomized clinical trial to evaluate teh efficacy of Coq10, Omega-3 supplement on periodontal parameters in chronic periodontitis patients, total antioxidant capacity in saliva after 2 months of administration;75 patients to department of periodontics were selected from teh patients referred to Broujerd dental school of teh Islamic Azad University of Medical Sciences; before commencing teh study, several clinical periodontal parameters were evaluated, including plaque index, bleeding on probing, gingival index, probing depth, and clinical attachment level(CAL) in six different areas of teh tooth surface; subsequently, scaling and root planning(SRP) were performed, and oral hygiene practices were improved for all participants. Teh subjects were then randomly assigned to three groups: Group A received 30 mg of CoQ10, Group B was given 200 mg of Omega-3 daily supplements, and Group C did not receive any medication; after teh two-month study period, teh clinical periodontal parameters were reassessed. Additionally, to compare teh total antioxidant capacity in saliva before and after teh intake of these supplements, as well as in patients who did not receive any medication, 2 ml of non-stimulated saliva was collected from each participant at teh beginning and end of teh study for analysis using UV-spectrophotometric methods, furthermore, teh following criteria determined teh selection of eligible participants for this study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06358963
Study type Interventional
Source Islamic Azad University, Tehran
Contact
Status Enrolling by invitation
Phase N/A
Start date February 20, 2024
Completion date May 10, 2024
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