Evaluation of Bone Metabolism Biomarkers in Periodontal Diseases

Status Completed

Clinical Trial Summary

This study evaluates the levels of biomarkers associated with bone metabolism in patients with different periodontal conditions.

Clinical Trial Description

Background: In this study, the levels of bone metabolism markers found in the saliva of individuals with different periodontal conditions were compared and the relationship of these markers with periodontal status was examined. Method: A total of 60 individuals, 20 with periodontitis (P), 20 with gingivitis (G), and 20 with periodontal healthy (S), were included in the study. Periodontal clinical parameters (plaque index, gingival index, bleeding on probing, clinical attachment level and probing pocket depth) and saliva samples were obtained from the individuals. Bone metabolism biomarker (necrotizing factor (TNF)-α, osteoprotegerin (OPG), nuclear factor kappa-β receptor activator ligand (RANKL) and sclerostin) levels in saliva samples were evaluated by enzyme-linked immunosorbent assay (ELISA). ;

Study Design

Related Conditions & MeSH terms

Periodontal Diseases

Clinical Trial Details

NCT number	NCT05702892
Study type	Interventional
Source	Necmettin Erbakan University
Contact
Status	Completed
Phase	N/A
Start date	November 5, 2020
Completion date	November 5, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT04712630` - Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft	N/A
Recruiting	`NCT03997552` - NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration	N/A
Completed	`NCT04478864` - Knowledge, Practice and State of Periodontal Health
Completed	`NCT03507868` - YKL-40 and IL-6 Levels in Periodontal Disease
Completed	`NCT05720481` - Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels	N/A
Recruiting	`NCT06052150` - Oral Health In Cirrhosis of the Liver (ORACLE)
Recruiting	`NCT06025955` - Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.	N/A
Recruiting	`NCT03510702` - SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
Completed	`NCT05631600` - Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study	Phase 2/Phase 3
Active, not recruiting	`NCT05068778` - Development of an AI App to Improve Compliance in Periodontal Maintenance Patients
Not yet recruiting	`NCT05178563` - Mechanisms of Acute Inflammation Following Periodontal Treatment	N/A
Recruiting	`NCT06086821` - Clinical Relevance of Different Time of Periodontal Re-evaluation	N/A
Recruiting	`NCT06224699` - Toothpaste With Sodium Carbonate in Patients With Gingivitis	N/A
Not yet recruiting	`NCT05721313` - Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study	N/A
Completed	`NCT06040944` - Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
Completed	`NCT06306937` - Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
Recruiting	`NCT04669717` - Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies	Phase 4
Completed	`NCT05576142` - Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
Not yet recruiting	`NCT03588507` - Clinical and Radiographic Evaluation of PPF With or Without NCHA Bone in Treatment of Intrabony Defects	N/A
Completed	`NCT04017078` - Assessment of Carotid Artery Calcifications