Clinical Trials Logo
  1. Home
  2. Periodontal Diseases
  3. NCT05341245
  4. Details
NCT05341245 Clinical Trial

Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects

Periodontal Diseases Clinical Trial

Official title:
Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects: A Randomized Experimental Study With Histomorphometric Analysis

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05341245
Other study ID # 1091
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date May 1, 2022
Est. completion date June 1, 2023

Study information
Verified date April 2022
Source Ain Shams University
Contact Zeiad Rashad
Phone 2001111309030
Email Zeiadkhaled2010@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Using Graphene oxide in the surgical management of periodontal intrabony defects.

Description:

Evaluation of the effect of Graphene oxide in the surgical management of periodontal intrabony defects in animals in periodontal clinical parameters with histomorphometric evaluation .

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 6
Est. completion date June 1, 2023
Est. primary completion date May 1, 2023
Accepts healthy volunteers No
Gender Male
Age group 1 Year to 2 Years
Eligibility Inclusion Criteria: - male dogs - 12-24 months old with approximate weight of 20-30 kg and general good health will be used Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Graphene oxide and open flap debridement
Using Graphene oxide with open flap debridement in management of periodontal intrabony defects in dogs
• Open flap debridement
Using Open flap debridement in management of periodontal intrabony defects in dogs

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Outcome
Type Measure Description Time frame Safety issue
Primary periodontal probing depth To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in periodontal probing depth "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe ). 2 months
Primary Clinical attachment level To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in clinical attachment level "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe ) 2 month
Secondary Histomorphometric evaluation To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects using histological sections obtained from the surgical site to do quantitative assessment of bone remodeling, modeling, and structure by "counting the number of osteoblasts and the number of bone trabeculae " using computer based microscope and software. 2 months
See also
  Status Clinical Trial Phase
Completed NCT04712630 - Non-Incised Papillae Surgical Approach (NIPSA) With and Without Graft N/A
Recruiting NCT03997552 - NIPSA Versus Marginal Approach by Palatal Incision and MIST in Periodontal Regeneration N/A
Completed NCT04478864 - Knowledge, Practice and State of Periodontal Health
Completed NCT03507868 - YKL-40 and IL-6 Levels in Periodontal Disease
Completed NCT05720481 - Impact of Periodontal Treatment on Growth Differentiation Factor-15 Levels N/A
Recruiting NCT06052150 - Oral Health In Cirrhosis of the Liver (ORACLE)
Recruiting NCT06025955 - Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement. N/A
Recruiting NCT03510702 - SCREENING OF EPIGENETIC BIOMARKERS (miRNAs) IN THE GINGIVAL SULCUS
Completed NCT05631600 - Manuka Honey as an Adjunct to Non-surgical Periodontal Therapy: Clinical Study Phase 2/Phase 3
Active, not recruiting NCT05068778 - Development of an AI App to Improve Compliance in Periodontal Maintenance Patients
Not yet recruiting NCT05178563 - Mechanisms of Acute Inflammation Following Periodontal Treatment N/A
Recruiting NCT06224699 - Toothpaste With Sodium Carbonate in Patients With Gingivitis N/A
Recruiting NCT06086821 - Clinical Relevance of Different Time of Periodontal Re-evaluation N/A
Not yet recruiting NCT05721313 - Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary Study N/A
Completed NCT06306937 - Serum Levels of Vitamin D and IL8 in Patients With Periodontitis
Completed NCT06040944 - Antipsychotic Induced Hyperprolactinemaia as Risk Factor for Periodontitis in Schizophrenic Patients
Recruiting NCT04669717 - Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies Phase 4
Completed NCT05576142 - Oral Findings in Pediatric Patients With Allergic Rhinitis and/or Asthma
Completed NCT03694496 - The Effectiveness of an Oral Health Education Programme of Adolescents in Hong Kong N/A
Completed NCT04017078 - Assessment of Carotid Artery Calcifications