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NCT05341245 Clinical Trial

Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects

Periodontal Diseases Clinical Trial

Official title:
Graphene Oxide in the Surgical Management of Intrabony Periodontal Defects: A Randomized Experimental Study With Histomorphometric Analysis

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT05341245
Other study ID # 1091
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date May 1, 2022
Est. completion date June 1, 2023

Study information
Verified date April 2022
Source Ain Shams University
Contact Zeiad Rashad
Phone 2001111309030
Email Zeiadkhaled2010@gmail.com
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Using Graphene oxide in the surgical management of periodontal intrabony defects.

Description:

Evaluation of the effect of Graphene oxide in the surgical management of periodontal intrabony defects in animals in periodontal clinical parameters with histomorphometric evaluation .

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 6
Est. completion date June 1, 2023
Est. primary completion date May 1, 2023
Accepts healthy volunteers No
Gender Male
Age group 1 Year to 2 Years
Eligibility Inclusion Criteria: - male dogs - 12-24 months old with approximate weight of 20-30 kg and general good health will be used Exclusion Criteria: -

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Graphene oxide and open flap debridement
Using Graphene oxide with open flap debridement in management of periodontal intrabony defects in dogs
• Open flap debridement
Using Open flap debridement in management of periodontal intrabony defects in dogs

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Ain Shams University

Outcome
Type Measure Description Time frame Safety issue
Primary periodontal probing depth To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in periodontal probing depth "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe ). 2 months
Primary Clinical attachment level To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects regarding the changes in clinical attachment level "measured in mm " using University of North Carolina periodontal probe( UNC 15 probe ) 2 month
Secondary Histomorphometric evaluation To evaluate the use of Graphene Oxide in the surgical management of intrabony periodontal defects using histological sections obtained from the surgical site to do quantitative assessment of bone remodeling, modeling, and structure by "counting the number of osteoblasts and the number of bone trabeculae " using computer based microscope and software. 2 months
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