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Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms

Periodontal Diseases Clinical Trial

Official title:
Development of a Molecular Diagnosing Platform for Relieving Periodontal Symptoms

Clinical Trial Summary

More than ninety percent of adults in Taiwan are suspected to carry periodontal disease, which causes bad breath, swollen and bleeding gums, plaque and even tooth loss. Half of the patients, however, are ignorance these clinical syndromes because of no obvious pain. In this study, the investigators selected six periodontal disease-associated bacteria strains, including Porphyromonas gingivalis (Pg), Fusobacterium nucleatum (Fn), Actinobacillus actinomycetemcomitans (Aa), Tannerella forsythia (Tf), Treponema denticola (Td) and Prevotella intermedia (Pi) as diagnostic markers. Using real-time PCR and MALDI Biotyper, the investigators will establish the database of oral microorganisms in Taiwanese people, providing periodontal disease clinical markers of high-risk groups and the basis for personal medicine of therapy in the future.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03345329
Study type Observational
Source General Biologicals Corporation
Contact
Status Completed
Phase N/A
Start date October 1, 2015
Completion date September 30, 2016
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