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Periodontal Attachment Loss clinical trials

View clinical trials related to Periodontal Attachment Loss.

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NCT ID: NCT03098498 Recruiting - Periodontitis Clinical Trials

Impact of Debridement Invasiveness on Attachment Gain After Antiinfective Periodontal Therapy

ATTGAIN16
Start date: June 1, 2016
Phase: N/A
Study type: Interventional

This study compared the gain of periodontal attachment after concomitant one-stage removal of bacterial biofilms and subgingival calculus with a two-stage procedure removing subgingival calculus 6 weeks after the initial removal of soft subgingival bacterial biofilms.

NCT ID: NCT03073174 Completed - Periodontal Pocket Clinical Trials

Dietary Intakes and Periodontal Health: A Follow-Up Study

Start date: January 1, 2017
Phase:
Study type: Observational

A previous study, on which this study is based, found that a diet higher in fruits and vegetables, beta-carotene, vitamin C, alpha-tocopherol, and fish oils (specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)) was positively associated with periodontal healing after sanative therapy (NCT02291835). The investigator's next step, in the present study, is to determine long-term benefits of sanative therapy in which patients have regular maintenance hygiene cleanings on periodontal health. Specifically, the relationship between intakes of specific foods, nutrients and supplements with clinical periodontal outcomes will be studied.

NCT ID: NCT03073161 Completed - Periodontal Pocket Clinical Trials

Flavonoid Intake and Periodontal Healing

Start date: January 1, 2017
Phase:
Study type: Observational

Periodontitis is a chronic inflammatory disease that, if untreated, will lead to tooth loss. To treat periodontal disease, sanative therapy is used as a first line cost-effective strategy to manage periodontal disease and thus prevent tooth loss. Diet is emerging as a modifiable factor that may help an individual to more fully respond to treatments such as sanative therapy. Dietary flavonoids, abundant in fruits and tea, may be particularly beneficial. Patients with moderate to severe chronic generalized periodontitis and undergoing sanative therapy will be recruited for the study. Mean clinical attachment loss as well as other clinical measures will be assessed at baseline and 8 to 12 weeks following sanative therapy to measure periodontal healing. At baseline and follow-up appointment, the following will be assessed to examine associations with clinical measures of periodontal healing: intakes of macronutrients and micronutrients, fruits, vegetables and tea as well as supplement use and salivary markers of inflammation.

NCT ID: NCT03027050 Completed - Periodontitis Clinical Trials

T-PRF Provides Advantages on Periodontal Healing: A Split Mouth Clinical Study

Start date: November 2015
Phase: N/A
Study type: Interventional

It was aimed to evaluate the contributions of T-PRF treatment combined with open flap debridement on biological markers in GCF and periodontal outcomes in chronic periodontitis patients. 29 patients (58 sites) with chronic periodontitis were treated either with autologous T-PRF with OFD or OFD alone. GCF growth factor levels and relative RANKL/OPG ratio at baseline and 2, 4 and 6 weeks postoperatively were analyzed, and clinical parameters such as probing depth (PD), relative attachment level (RAL) and gingival margin level (GML) at baseline and 9 months after surgery were compromised.

NCT ID: NCT02666573 Completed - Clinical trials for Periodontal Diseases

Photodynamic Therapy During Supportive Periodontal Therapy

Start date: June 2013
Phase: Phase 4
Study type: Interventional

27 subjects on SPT, each with at least two residual pockets ≥5mm, were recruited for this randomised, split-mouth controlled trial, providing a total of 72 sites. At baseline, probing pocket depth (PPD), recession, clinical attachment level (CAL), plaque and bleeding on probing (BOP) of all sites were examined. Gingival crevicular fluid (GCF) were collected to determine level of cytokines IL-1β, -6, -8, TNF-α and MMP-8 via ELISA. Control sites received subgingival instrumentation and rubber cup polishing with pumice. In addition test sites received a single application of PDT using Fotosan® and photosensitizer consisting of toludine blue O solution. The subjects were recalled three and six months later and re-examined. Site level analysis was performed.

NCT ID: NCT00757159 Completed - Periodontal Disease Clinical Trials

Study on Regenerative Treatment of Intra-bony Defects

Start date: August 2008
Phase: Phase 4
Study type: Interventional

The aim of this investigation is to determine whether a synthetic hydroxyapatite is as effective as an enamel matrix protein for periodontal regeneration in patients who have intra-bony periodontal defects.

NCT ID: NCT00734708 Completed - Periodontitis Clinical Trials

Phase 3 Clinical Trial of Periodontal Tissue Regeneration Using Fibroblast Growth Factor-2(Trafermin)

Start date: August 2008
Phase: Phase 3
Study type: Interventional

This study aims to verify the effectiveness of Trafermin (recombinant human basic fibroblast growth factor) in stimulating regeneration of periodontal tissue lost by periodontitis and to evaluate the safety of such stimulation.

NCT ID: NCT00632957 Completed - Clinical trials for Periodontal Attachment Loss

Oral Infections: Dietary Regulation of Local and Systemic Inflammatory Responses

Start date: September 2004
Phase: N/A
Study type: Interventional

The purpose of this study is to test the hypothesis that dietary n-3 PUFA will have a beneficial effect on systemic and local markers of inflammation when combined with traditional, non-surgical periodontal therapy.