Pelvic Pain Syndrome Clinical Trial
Official title:
MRI & MRV in Pelvic Congestion Syndrome in Females
To investigate the feasibility of MRI and MRV in diagnosis of pelvic congestion syndrome.
In the past, a diagnosis of chronic pelvic pain left many women frustrated with few treatment
options and a lack of available resources. Their physicians were likewise perplexed, despite
the endless acquisition of negative laboratory and imaging data as well as inconclusive
consultations obtained. In the last 10 years, improved scientific understanding and increased
physician awareness have lessened the confusion surrounding this condition and its distinct
association with pelvic congestion syndrome (PCS). Furthermore, refinements of medical and
minimally invasive surgical solutions give affected patients more therapeutic choices today.
Since anatomical venous variations in the pelvis are common, it is important to know the
anatomy of these vessels for treatment planning. Imaging is critical in the evaluation of
pelvic varices, both to differentiate them from other condition and also because pelvic
varices may be secondary to serious underlying pathology, such as inferior vena caval
obstruction, portal hypertension, increased pelvic blood flow, and vascular malformations.
The diagnosis of PCS has usually been suggested by duplex ultrasound (US), but ultrasound
imaging does not readily show the gonadal veins. Phlebography is the "gold standard" for
anatomic diagnostic studies. Related mortality and morbidity are low, but patient discomfort
and costs make this an unattractive routine method of diagnosis. Magnetic resonance imaging
(MRI) can usually demonstrate pelvic and ovarian varices, as well as the gonadal veins.
In this prospective study, we will investigate the feasibility of using magnetic resonance
venography (MRV) in the diagnosis of PCS and evaluated its accuracy and reliability in
comparison to phlebography.
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