Pelvic Cancer Clinical Trial
— MRI-RP-2021Official title:
Post-radiotherapy MRI Based AI System to Predict Radiation Proctitis for Pelvic Cancers
In this study, investigators utilize a Artificial Intelligence (AI) supportive system to predict radiation proctitis for patients with pelvic cancers underwent radiotherapy. By the system, whether the participants achieve the radiation proctitis will be identified based on the radiomics features extracted from the post radiotherapy Magnetic Resonance Imaging (MRI) . The predictive power to discriminate the radiation proctitis individuals from non-radiation proctitis patients, will be validated in this multicenter, prospective clinical study.
Status | Not yet recruiting |
Enrollment | 400 |
Est. completion date | August 1, 2024 |
Est. primary completion date | June 1, 2024 |
Accepts healthy volunteers | |
Gender | All |
Age group | 18 Years to 75 Years |
Eligibility | Inclusion Criteria: - pathologically diagnosed as pelvic tumours - intending to receive or undergoing radiotherapy - MRI (high-solution T2-weighted imaging, contrast-enhanced T1-weighted imaging, and diffusion-weighted imaging are required) examination is completed after radiotherapy Exclusion Criteria: - insufficient imaging quality of MRI (e.g., lack of sequence, motion artifacts) - incomplete radiotherapy |
Country | Name | City | State |
---|---|---|---|
China | the Sixth Affiliated Hospital of Sun Yat-sen University | Guangzhou | Guangdong |
China | the Sixth Affiliated Hospital of Sun Yat-sen University | GuangZhou | Guangdong |
China | Sir Run Run Shaw Hospital | HangZhou | Zhejiang |
China | The Third Affiliated Hospital of Kunming Medical College | Kunming | Yunnan |
Lead Sponsor | Collaborator |
---|---|
Sixth Affiliated Hospital, Sun Yat-sen University |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | The sensitivity of AI prediction system in prediction the radiation proctitis candidates | The sensitivity of AI prediction system in identifying the radiation proctitis candidates from non-radiation proctitis individuals among pelvic cancers underwent radiotherapy | baseline | |
Primary | The area under curve (AUC) of Receiver Operating Characteristic (ROC) curves of AI prediction system in prediction radiation proctitis | The area under curve (AUC) of Receiver Operating Characteristic (ROC) curves of AI prediction system in identifying the radiation proctitis candidates from non-radiation proctitis individuals among pelvic cancers underwent radiotherapy | baseline | |
Secondary | The specificity of AI prediction system in prediction radiation proctitis | The specificity of AI prediction system in identifying the radiation proctitis candidates from non-radiation proctitis individuals among pelvic cancers underwent radiotherapy | baseline |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT04553471 -
Palliative Lattice Stereotactic Body Radiotherapy (SBRT) for Patients With Sarcoma, Thoracic, Abdominal, and Pelvic Cancers
|
N/A | |
Completed |
NCT04070950 -
Sexuality of Women With Pelvic Cancer
|
||
Active, not recruiting |
NCT05269186 -
Interest of Virtual Reality on Anxiety Before the Planning CT Scan in Radiotherapy
|
N/A | |
Recruiting |
NCT00493688 -
A Study to Determine Whether Perioperative Energy Dynamics Correlates With Postoperative Outcomes
|
||
Terminated |
NCT04199754 -
IV Contrast-Enhanced Cone Beam Computed Tomography (CBCT) in Radiotherapy
|
Early Phase 1 | |
Recruiting |
NCT03804333 -
Short Course Radiation Therapy in Palliative Treatment of Pelvic Cancer
|
N/A | |
Completed |
NCT00028405 -
Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors
|
Phase 1 | |
Not yet recruiting |
NCT06187103 -
Evaluation of Improved Onboard Patient Imaging
|
N/A | |
Recruiting |
NCT05219058 -
Reconstruction in Extended MArgin Cancer Surgery
|
||
Recruiting |
NCT05610501 -
Ultrasound-guided Tru-Cut Biopsy in Pelvic Masses.
|
||
Completed |
NCT00437372 -
Phase IB Study Using Sunitinib Plus Radiation Therapy for Cancer Patients
|
Phase 1 | |
Completed |
NCT05524454 -
Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
|
N/A | |
Completed |
NCT03757858 -
Hyperthermia Combined With Immunotherapy in the Treatment of Abdominal and Pelvic Malignancies or Metastases
|
Phase 1/Phase 2 | |
Recruiting |
NCT06397573 -
Ablative Stereotactic MR-Guided Adaptive Reirradiation
|
N/A | |
Completed |
NCT03242538 -
Prehabilitation for Pelvic Cancer: Changes in Setup Variability
|
N/A | |
Not yet recruiting |
NCT06458725 -
Assessment of DW-MRI Measures : Reproducibility and Repeatability in Pelvic Imaging on MR-Linac With Healthy Volunteers
|
N/A | |
Completed |
NCT05074082 -
Perineal Flap Reconstruction Following Surgery for Advanced Pelvic Malignancy
|
||
Recruiting |
NCT04344899 -
Pediatric Oncology Recovery Trial After Surgery
|
||
Recruiting |
NCT03595722 -
Exploring HIFU as a Treatment for Rectal and Other Pelvic Cancers
|
N/A | |
Completed |
NCT05074069 -
A Review of Functional and Surgical Outcomes of Gynaecological Reconstruction in the Context of Pelvic Exenteration
|