Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity

Pediatric obésity Clinical Trial

— TIMEX2  

Official title:

Effect of the Exercise-meal Timing on Energy Intake and Appetite in Adolescents With Obesity: the TIMEX 2 Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03967782
• Other study ID #: RBHP 2019 BOIRIE
• Secondary ID: 2019-A00507-50
• Status: Completed
• Phase: N/A
• Start date: August 31, 2019
• Est. completion date: October 30, 2019

Study information

• Verified date: October 2019
• Source: University Hospital, Clermont-Ferrand
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of the present study is to compare the effect of realizing an exercise right before or right after a meal of on energy intake, appetite feelings and food reward in adolescents with obesity.

Description:

The present study will compare the nutritional response to the realisation of an acute exercise right before or right after lunch in adolescents with obesity. 18 adolescents with obesity will be asked to randomly complete three experimental sessions: i) one control session (rest); ii) one session with an acute exercise realized right before lunch; iii) one session with an acute exercise realized right after lunch. Their ad libitum energy intake will be assessed during lunch as well as at dinner time. Appetite feelings will be assessed at regular intervals and their food reward in response to the lunch will also be assessed.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 17
• Est. completion date: October 30, 2019
• Est. primary completion date: September 29, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 12 Years to 16 Years

Eligibility

Inclusion Criteria:

• BMI percentile > 97th percentile according to the french curves.

• ages 12-16 years old

• Signed consent form

• being registered in the national social security system

• no contraindication to physical activity

Exclusion Criteria:

• Previous surgical interventions that is considered as non-compatible with the study.

• Diabetes

• weight loss during the last 6 months

• cardiovascular disease or risks

Related Conditions & MeSH terms

• Obesity
• Pediatric Obesity
• Pediatric obésity

Intervention

Behavioral:
• CON
Control condition without exercise / rest condition. The adolescents will be asked to remain quiet and at rest during the morning and will receive an ad libitum meal at lunch and dinner times. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
• EX-MEAL
Condition with an acute exercise set right before lunch The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) right before ad ad libitum lunch meal. Lunch will be served ad libitum as well as diner. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.
• MEAL-EX
. condition with an acute exercise set right after lunch. The adolescents will be asked to complete a 30 minutes exercise set at 65% of their capacities (cycling) right after an ad libitul buffet meal. Lunch will be served ad libitum as well as diner. Their food reward will be assessed before and after lunch. Their appetite feelings will be assessed at regular intervals.

Locations

Country	Name	City	State
France	Chu Clermont Ferrand	Clermont-Ferrand

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Clermont-Ferrand	AME2P Laboratory, Clermont Auvergne University

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in energy intake measured during an ad libitum buffet meal (in kcal)	food intake will be measured ad libitum during a lunch buffet. The adolescents will be offered an ad libitum buffet-type meal composed based on their food intake preferences. Their intake will be weighted using an electronic food scale by a member of the investigation team and then analysed using Bilnuts software.	day 1 , day 8, day 15
Secondary	Hunger feelings	hunger area under the curve will be assessed using visual analogue scale through a the day	day 1 , day 8, day 15
Secondary	Food reward	The participants will be asked to complete a validated computer-based procedure to measure food reward (Leeds Food Preference Questionnaire; LFPQ) (Finlayson, King et al. 2008).	day 1 , day 8, day 15