Effect of Folate Acid on Offspring Obesity

Pediatric Obesity Clinical Trial

Official title:

Mechanism of Folate Acid in Influencing Offspring Obesity During Pregnancy

Clinical Trial Details — Status: Enrolling by invitation

Administrative data

• NCT number: NCT02236208
• Other study ID #: NMU-530604-XG1
• Status: Enrolling by invitation
• Phase: N/A
• First received: September 2, 2014
• Last updated: September 9, 2014
• Start date: May 2013
• Est. completion date: May 2015

Study information

• Verified date: September 2014
• Source: Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Health authority: China: Ethics Committee
• Study type: Observational

Clinical Trial Summary

The purpose of this study is to observe the effect of lack or excess of folic acid in first, second and third trimester on child birth weight, fat content and the secretion of metabolism related hormone, and clinical follow-up their offspring obesity.

Recruitment information / eligibility

• Status: Enrolling by invitation
• Enrollment: 20000
• Est. completion date: May 2015
• Est. primary completion date: May 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Pregnancy women

• children

• Chinese

Exclusion Criteria:

Study Design

Observational Model: Cohort, Time Perspective: Prospective

Related Conditions & MeSH terms

• Obesity
• Pediatric Obesity

Locations

Country	Name	City	State
China	Nanjing Maternal and Child Health Care Hospital Affiliated to Nanjing Medical University	Nanjing	Jiangsu

Sponsors (1)

Lead Sponsor	Collaborator
Nanjing Medical University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The level of folate acid of pregnancy women at first trimester		12 weeks of pregnancy	Yes
Secondary	The level of folate acid of pregnancy women at second trimester		20-24 weeks of pregnancy	Yes
Secondary	The level of folate acid of pregnancy women at third trimester		28-40 weeks of pregnancy	Yes
Secondary	The birth weight, fat content and metabolism related hormone secretion of their offspring		At birth	Yes
Secondary	The weight, fat content and metabolism related hormone secretion of their offspring at one year old		One years old	Yes
Secondary	The weight, fat content and metabolism related hormone secretion of their offspring at 3 years old		3 years old	Yes
Secondary	The weight, fat content and metabolism related hormone secretion of their offspring at 5-7 years old		5-7 years old	Yes
Secondary	The weight, fat content and the secretion of metabolism related hormone of offspring at 18 years old		18 years old	Yes